[Hub]/) : Traits : Arm fat mass (left) :

chr11:118,241,995-120,797,604

Best TWAS P=1.09e-08 · Best GWAS P=8.6e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NLRX1 0.04 0.03 enet 14 0.02 1.2e-03 4.2 5.5 4.8e-08 -0.08 0.17 0.40 TRUE
2 GTEx Adipose Subcutaneous HMBS 0.22 0.14 lasso 3 0.16 1.1e-12 -5.3 -5.3 9.1e-08 0.97 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum RP11-110I1.14 0.14 0.09 lasso 4 0.09 2.5e-05 -5.2 5.5 3.6e-08 -0.93 0.02 0.97 FALSE
4 GTEx Adrenal Gland HMBS 0.24 0.17 lasso 5 0.18 7.2e-07 -5.2 -5.1 3.0e-07 0.98 0.01 0.99 FALSE
5 GTEx Artery Aorta HMBS 0.24 0.14 enet 15 0.17 1.6e-09 -5.2 -5.3 1.4e-07 0.95 0.01 0.99 FALSE
6 GTEx Artery Coronary HMBS 0.27 0.19 lasso 4 0.17 2.3e-06 -5.2 -5.3 1.1e-07 0.97 0.01 0.98 FALSE
7 GTEx Brain Caudate basal ganglia VPS11 0.35 0.24 lasso 5 0.21 1.5e-06 -5.2 5.3 1.5e-07 -0.95 0.02 0.98 FALSE
8 GTEx Brain Cerebellum HMBS 0.21 0.15 lasso 3 0.15 3.3e-05 -5.1 -5.2 1.8e-07 0.98 0.01 0.97 FALSE
9 GTEx Brain Cortex HMBS 0.22 0.12 lasso 1 0.11 6.5e-04 -5.1 -5.1 2.8e-07 0.97 0.02 0.89 FALSE
10 GTEx Brain Hippocampus VPS11 0.37 0.13 lasso 4 0.11 1.4e-03 -5.1 5.2 2.2e-07 -0.98 0.02 0.87 FALSE
11 GTEx Brain Nucleus accumbens basal ganglia VPS11 0.37 0.19 lasso 8 0.30 9.4e-09 -5.1 5.1 3.3e-07 -0.79 0.02 0.94 FALSE
12 GTEx Breast Mammary Tissue OAF 0.19 0.00 enet 23 0.02 4.2e-02 5.0 5.1 3.0e-07 -0.10 0.02 0.83 TRUE
13 GTEx Breast Mammary Tissue HMBS 0.20 0.08 lasso 8 0.08 6.0e-05 -5.1 -5.1 3.0e-07 0.96 0.02 0.98 FALSE
14 GTEx Cells EBV-transformed lymphocytes HMBS 0.26 0.13 lasso 5 0.10 3.8e-04 -5.2 -5.3 1.2e-07 0.97 0.01 0.97 FALSE
15 GTEx Cells Transformed fibroblasts HMBS 0.31 0.25 lasso 7 0.25 1.0e-18 -5.2 -5.2 2.6e-07 0.95 0.01 0.99 FALSE
16 GTEx Esophagus Mucosa HMBS 0.26 0.18 lasso 5 0.18 3.9e-12 -5.2 -5.5 4.0e-08 0.97 0.01 0.98 FALSE
17 GTEx Lung HMBS 0.18 0.14 lasso 3 0.14 1.6e-10 -5.3 -5.3 9.7e-08 0.97 0.01 0.99 FALSE
18 GTEx Muscle Skeletal HMBS 0.12 0.12 lasso 3 0.12 3.7e-12 -5.2 -5.3 1.4e-07 0.97 0.01 0.99 FALSE
19 GTEx Muscle Skeletal RP11-110I1.14 0.24 0.12 lasso 9 0.15 2.4e-14 -5.2 5.5 3.5e-08 -0.95 0.01 0.98 FALSE
20 GTEx Pancreas HMBS 0.25 0.21 enet 10 0.20 6.9e-09 -5.2 -5.4 6.6e-08 0.94 0.01 0.99 FALSE
21 GTEx Pituitary VPS11 0.23 0.16 lasso 3 0.20 9.2e-06 -5.4 5.1 2.9e-07 -0.91 0.02 0.94 FALSE
22 GTEx Skin Not Sun Exposed Suprapubic HMBS 0.24 0.18 lasso 6 0.18 4.5e-10 -5.2 -5.4 8.1e-08 0.96 0.01 0.99 FALSE
23 GTEx Small Intestine Terminal Ileum HMBS 0.49 0.27 enet 17 0.18 9.0e-05 -5.4 -5.5 4.6e-08 0.98 0.01 0.97 FALSE
24 GTEx Thyroid VPS11 0.19 0.12 lasso 6 0.09 1.7e-07 -5.2 5.2 1.7e-07 -0.97 0.01 0.98 FALSE
25 GTEx Thyroid HMBS 0.22 0.20 enet 10 0.22 2.2e-16 -5.2 -5.3 1.4e-07 0.97 0.01 0.99 FALSE
26 GTEx Thyroid RP11-110I1.14 0.16 0.13 lasso 3 0.12 9.0e-10 -5.2 5.2 1.5e-07 -0.98 0.01 0.98 FALSE
27 GTEx Vagina HMBS 0.23 0.14 lasso 4 0.12 1.1e-03 -5.3 -5.7 1.1e-08 0.96 0.02 0.88 TRUE
28 METSIM Adipose HMBS 0.12 0.07 lasso 8 0.07 3.0e-10 -5.2 -5.2 2.6e-07 0.97 0.02 0.98 FALSE
29 ROSMAP Brain Pre-frontal Cortex VPS11 0.25 0.17 lasso 5 0.18 5.0e-23 -5.4 5.2 1.7e-07 -0.95 0.00 1.00 FALSE
30 TCGA Prostate Tumor HMBS 0.23 0.14 lasso 1 0.14 4.8e-17 -5.2 -5.2 1.9e-07 0.96 0.00 0.99 FALSE