[Hub]/) : Traits : Arm fat mass (left) :

chr12:89,116,708-90,682,621

Best TWAS P=8.29e-12 · Best GWAS P=2.83e-14 conditioned to 5.03e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous POC1B 0.12 0.08 lasso 9 0.09 1.7e-07 -5.5 6.1 1.4e-09 -0.31 0.98 0.01 FALSE
2 GTEx Adrenal Gland RP11-981P6.1 0.33 0.29 lasso 3 0.19 2.2e-07 -5.5 -5.9 4.6e-09 0.25 0.99 0.00 FALSE
3 GTEx Artery Tibial POC1B 0.13 0.06 enet 29 0.06 1.7e-05 -5.7 6.8 8.3e-12 -0.37 0.42 0.40 TRUE
4 GTEx Artery Tibial RP11-981P6.1 0.07 0.06 lasso 1 0.03 1.3e-03 -5.2 -5.2 2.3e-07 0.29 0.46 0.26 FALSE
5 GTEx Colon Sigmoid RP11-981P6.1 0.19 0.12 lasso 4 0.11 9.7e-05 -5.5 -5.1 3.1e-07 0.27 0.32 0.06 FALSE
6 GTEx Colon Transverse RP11-981P6.1 0.14 0.05 enet 26 0.05 1.9e-03 -5.6 -5.4 6.9e-08 0.23 0.32 0.23 FALSE
7 GTEx Esophagus Muscularis RP11-981P6.1 0.18 0.10 lasso 3 0.06 2.9e-04 -5.6 -5.5 4.5e-08 0.26 0.87 0.06 FALSE
8 GTEx Nerve Tibial POC1B 0.30 0.18 lasso 6 0.22 1.0e-15 4.4 5.9 4.2e-09 -0.27 1.00 0.00 FALSE
9 GTEx Spleen RP11-981P6.1 0.28 0.18 lasso 13 0.14 2.1e-04 -5.2 -5.7 1.1e-08 0.29 0.37 0.15 FALSE
10 GTEx Thyroid RP11-981P6.1 0.24 0.25 lasso 5 0.26 3.9e-20 -5.6 -5.7 1.6e-08 0.30 1.00 0.00 FALSE
11 METSIM Adipose POC1B 0.07 0.03 bslmm 381 0.03 5.2e-05 -5.6 5.1 3.4e-07 -0.35 0.92 0.00 FALSE