[Hub]/) : Traits : Arm fat mass (left) :

chr17:33,941,051-35,675,511

Best TWAS P=4.08e-15 · Best GWAS P=1.73e-13 conditioned to 0.0627

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DHRS11 0.22 0.24 bslmm 311 0.25 1.6e-30 7.2 -5.7 1.1e-08 0.62 0.02 0.98 FALSE
2 CommonMind Brain Pre-frontal Cortex MYO19 0.05 0.05 lasso 2 0.05 8.4e-07 6.7 -6.9 5.5e-12 0.82 0.04 0.95 FALSE
3 GTEx Adipose Subcutaneous GGNBP2 0.10 0.11 enet 9 0.11 3.5e-09 -7.1 7.5 4.9e-14 -0.92 0.03 0.97 FALSE
4 GTEx Adipose Subcutaneous MYO19 0.07 0.05 enet 10 0.03 1.3e-03 -7.3 -7.4 1.7e-13 0.94 0.02 0.98 FALSE
5 GTEx Adipose Visceral Omentum GGNBP2 0.13 0.12 enet 11 0.13 1.9e-07 6.9 7.4 1.1e-13 -0.80 0.04 0.96 FALSE
6 GTEx Artery Aorta GGNBP2 0.13 0.12 lasso 4 0.12 2.4e-07 7.2 7.3 2.6e-13 -0.82 0.03 0.97 FALSE
7 GTEx Artery Aorta DHRS11 0.10 0.07 lasso 5 0.06 2.7e-04 7.2 -7.3 3.6e-13 0.79 0.02 0.97 FALSE
8 GTEx Artery Aorta MYO19 0.20 0.16 enet 9 0.15 1.6e-08 6.7 -6.3 3.2e-10 0.88 0.02 0.98 FALSE
9 GTEx Artery Tibial GGNBP2 0.12 0.12 enet 15 0.12 1.2e-09 7.2 7.3 2.5e-13 -0.85 0.02 0.98 FALSE
10 GTEx Artery Tibial DHRS11 0.14 0.08 enet 11 0.11 7.1e-09 6.9 -6.9 5.9e-12 0.86 0.03 0.97 FALSE
11 GTEx Artery Tibial MYO19 0.12 0.11 lasso 6 0.13 4.1e-10 -7.2 -7.6 2.8e-14 0.93 0.03 0.97 FALSE
12 GTEx Brain Caudate basal ganglia DHRS11 0.18 0.12 lasso 4 0.02 9.2e-02 7.0 -7.2 7.5e-13 0.79 0.03 0.83 FALSE
13 GTEx Brain Cerebellar Hemisphere CTB-75G16.3 0.27 0.14 lasso 4 0.05 1.8e-02 7.1 7.2 6.6e-13 -0.73 0.03 0.77 FALSE
14 GTEx Brain Cerebellum DHRS11 0.33 0.23 lasso 4 0.20 1.9e-06 7.2 -7.2 6.1e-13 0.77 0.02 0.97 FALSE
15 GTEx Brain Cortex DHRS11 0.23 0.18 enet 24 0.18 8.5e-06 7.2 -7.0 2.7e-12 0.76 0.02 0.97 FALSE
16 GTEx Brain Cortex CTB-75G16.3 0.32 0.15 lasso 8 0.14 1.4e-04 6.7 5.2 1.7e-07 -0.70 0.14 0.55 FALSE
17 GTEx Brain Frontal Cortex BA9 DHRS11 0.34 0.26 enet 19 0.25 2.5e-07 7.2 -7.0 1.8e-12 0.76 0.02 0.97 FALSE
18 GTEx Brain Hypothalamus DHRS11 0.24 0.12 lasso 2 0.12 1.1e-03 7.0 -6.9 7.0e-12 0.84 0.03 0.87 FALSE
19 GTEx Brain Nucleus accumbens basal ganglia DHRS11 0.18 0.20 lasso 3 0.15 8.8e-05 7.0 -7.0 1.9e-12 0.77 0.03 0.94 FALSE
20 GTEx Breast Mammary Tissue GGNBP2 0.08 0.06 lasso 2 0.03 7.8e-03 6.7 7.4 9.7e-14 -0.73 0.03 0.84 FALSE
21 GTEx Cells EBV-transformed lymphocytes GGNBP2 0.13 0.15 lasso 2 0.13 5.5e-05 7.0 7.0 1.9e-12 -0.84 0.03 0.93 FALSE
22 GTEx Cells EBV-transformed lymphocytes DHRS11 0.14 0.08 enet 3 0.07 3.2e-03 7.1 -7.1 1.6e-12 0.84 0.03 0.83 FALSE
23 GTEx Cells EBV-transformed lymphocytes ZNHIT3 0.31 0.32 enet 9 0.22 1.1e-07 -7.3 -7.6 4.3e-14 0.92 0.01 0.99 FALSE
24 GTEx Cells Transformed fibroblasts GGNBP2 0.11 0.10 enet 12 0.10 4.5e-08 6.9 6.0 1.7e-09 -0.84 0.04 0.96 FALSE
25 GTEx Cells Transformed fibroblasts DHRS11 0.11 0.08 lasso 2 0.08 2.7e-06 7.2 -6.6 4.2e-11 0.75 0.02 0.98 FALSE
26 GTEx Cells Transformed fibroblasts ZNHIT3 0.15 0.07 lasso 7 0.05 1.7e-04 -7.1 -6.8 1.3e-11 0.91 0.03 0.95 FALSE
27 GTEx Colon Transverse GGNBP2 0.15 0.15 enet 13 0.11 4.8e-06 7.2 6.5 1.0e-10 -0.78 0.02 0.97 FALSE
28 GTEx Colon Transverse MYO19 0.13 0.12 lasso 2 0.11 8.0e-06 -7.4 -7.0 2.3e-12 0.98 0.01 0.99 FALSE
29 GTEx Esophagus Gastroesophageal Junction GGNBP2 0.12 0.12 lasso 2 0.09 4.9e-04 7.2 7.2 4.7e-13 -0.77 0.02 0.93 FALSE
30 GTEx Esophagus Mucosa GGNBP2 0.16 0.16 enet 15 0.18 3.1e-12 6.6 7.7 1.7e-14 -0.88 0.04 0.96 FALSE
31 GTEx Esophagus Mucosa DHRS11 0.12 0.08 lasso 2 0.06 5.1e-05 -7.4 -7.6 2.4e-14 0.97 0.02 0.98 FALSE
32 GTEx Esophagus Mucosa ZNHIT3 0.22 0.13 enet 15 0.08 8.1e-06 -7.3 -6.1 1.2e-09 0.84 0.02 0.98 FALSE
33 GTEx Esophagus Mucosa MYO19 0.11 0.08 enet 12 0.04 1.2e-03 -7.3 -6.8 1.4e-11 0.92 0.02 0.98 FALSE
34 GTEx Esophagus Muscularis GGNBP2 0.15 0.11 enet 13 0.14 1.4e-08 -7.1 6.5 6.0e-11 -0.82 0.03 0.97 FALSE
35 GTEx Esophagus Muscularis DHRS11 0.14 0.08 lasso 5 0.08 8.2e-06 6.9 -7.4 1.2e-13 0.94 0.02 0.97 FALSE
36 GTEx Esophagus Muscularis MYO19 0.14 0.14 enet 8 0.15 2.8e-09 -7.4 -7.3 2.7e-13 0.97 0.02 0.98 FALSE
37 GTEx Heart Atrial Appendage MYO19 0.13 0.12 lasso 1 0.11 1.1e-05 6.9 -6.9 3.9e-12 0.86 0.04 0.95 FALSE
38 GTEx Heart Left Ventricle DHRS11 0.13 0.10 lasso 1 0.08 3.3e-05 6.8 -6.8 7.8e-12 0.80 0.02 0.98 FALSE
39 GTEx Heart Left Ventricle MYO19 0.10 0.06 lasso 3 0.04 5.4e-03 -7.4 -7.1 1.7e-12 0.96 0.02 0.94 FALSE
40 GTEx Lung GGNBP2 0.08 0.01 enet 8 0.01 3.3e-02 -7.4 7.4 1.4e-13 -0.93 0.02 0.98 FALSE
41 GTEx Lung DHRS11 0.09 0.08 lasso 5 0.10 3.7e-08 6.9 -7.4 1.5e-13 0.86 0.02 0.98 FALSE
42 GTEx Lung MYO19 0.15 0.14 enet 8 0.13 2.1e-10 -7.3 -7.0 2.0e-12 0.93 0.02 0.98 FALSE
43 GTEx Muscle Skeletal GGNBP2 0.08 0.06 enet 14 0.05 2.5e-05 6.6 6.8 1.3e-11 -0.77 0.05 0.95 FALSE
44 GTEx Muscle Skeletal DHRS11 0.09 0.08 lasso 3 0.09 9.3e-09 6.9 -7.1 9.6e-13 0.82 0.04 0.96 FALSE
45 GTEx Muscle Skeletal MYO19 0.04 0.05 enet 14 0.03 6.4e-04 6.7 -6.4 1.7e-10 0.79 0.05 0.93 FALSE
46 GTEx Nerve Tibial GGNBP2 0.10 0.04 lasso 3 0.05 2.4e-04 -7.1 7.4 1.6e-13 -0.92 0.03 0.97 FALSE
47 GTEx Nerve Tibial MYO19 0.11 0.11 enet 8 0.08 1.4e-06 -7.2 -6.9 4.0e-12 0.92 0.02 0.98 FALSE
48 GTEx Pancreas GGNBP2 0.15 0.09 lasso 2 0.07 5.1e-04 7.0 7.1 1.0e-12 -0.82 0.03 0.96 FALSE
49 GTEx Skin Sun Exposed Lower leg GGNBP2 0.11 0.06 enet 11 0.10 1.3e-08 6.6 7.2 6.1e-13 -0.85 0.05 0.95 FALSE
50 GTEx Skin Sun Exposed Lower leg MYO19 0.07 0.01 enet 7 0.03 1.8e-03 -7.2 -6.7 1.7e-11 0.88 0.03 0.96 FALSE
51 GTEx Stomach GGNBP2 0.13 0.06 lasso 3 0.06 5.9e-04 6.7 7.1 1.6e-12 -0.81 0.03 0.94 FALSE
52 GTEx Testis GGNBP2 0.19 0.19 lasso 1 0.15 3.8e-07 6.8 6.8 7.8e-12 -0.80 0.03 0.97 FALSE
53 GTEx Testis ZNHIT3 0.27 0.33 lasso 2 0.32 8.0e-15 -7.3 7.2 5.7e-13 -0.93 0.01 0.99 FALSE
54 GTEx Thyroid GGNBP2 0.07 0.06 lasso 2 0.04 2.8e-04 7.2 7.4 1.0e-13 -0.82 0.02 0.98 FALSE
55 GTEx Thyroid MYO19 0.11 0.05 lasso 3 0.04 7.1e-04 6.7 -6.5 6.5e-11 0.79 0.04 0.91 FALSE
56 GTEx Whole Blood GGNBP2 0.08 0.01 lasso 4 0.01 3.6e-02 6.9 6.9 6.6e-12 -0.85 0.04 0.81 FALSE
57 METSIM Adipose GGNBP2 0.16 0.14 lasso 5 0.14 6.2e-21 -7.3 7.4 1.4e-13 -0.92 0.02 0.98 FALSE
58 METSIM Adipose MYO19 0.10 0.10 lasso 4 0.10 1.6e-14 -7.1 -7.3 2.1e-13 0.92 0.03 0.97 FALSE
59 NTR Blood GGNBP2 0.03 0.02 bslmm 331 0.02 7.7e-07 6.6 7.9 4.1e-15 -0.79 0.04 0.96 TRUE
60 YFS Blood DHRS11 0.05 0.06 lasso 7 0.06 2.5e-18 6.9 -7.3 3.4e-13 0.80 0.18 0.82 FALSE
61 YFS Blood GGNBP2 0.07 0.09 enet 21 0.10 4.7e-31 -7.2 6.7 2.5e-11 -0.90 0.02 0.98 FALSE
62 YFS Blood MYO19 0.12 0.14 enet 14 0.14 4.0e-45 -7.1 -6.9 4.1e-12 0.91 0.03 0.97 FALSE
63 TCGA Ovarian Tumor CCL4L1 0.03 0.02 blup 78 0.02 2.2e-03 -7.4 -5.8 8.1e-09 0.68 0.01 0.86 FALSE