TWAS
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Traits
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Traits
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Arm fat mass (left)
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chr6:125,370,626-126,767,600
Best TWAS P=1.39e-08 · Best GWAS P=1.34e-08 conditioned to 1
125.4M
125.6M
125.8M
126M
126.2M
126.4M
126.6M
126.8M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Testis
HEY2
0.31
0.17
lasso
5
0.19
7.4e-09
-5.7
-5.7
1.4e-08
0.99
0.01
0.99
TRUE
3
GTEx
Thyroid
HEY2
0.22
0.24
lasso
6
0.23
1.0e-17
-5.7
-5.5
3.3e-08
0.99
0.01
0.99
FALSE
1
CommonMind
Brain Pre-frontal Cortex
HEY2
0.15
0.20
lasso
10
0.21
6.7e-25
-5.6
-5.5
4.1e-08
0.99
0.01
0.99
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
HEY2
0.03
0.04
lasso
3
0.02
3.8e-03
5.1
-5.3
1.4e-07
0.90
0.02
0.97
FALSE