Best TWAS P=1.07e-08 · Best GWAS P=3.07e-09 conditioned to 0.037
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | SUPT3H | 0.27 | 0.10 | lasso | 7 | 0.06 | 3.4e-04 | 5.2 | -5.7 | 1.1e-08 | -0.84 | 0.09 | 0.91 | TRUE |
2 | GTEx | Esophagus Mucosa | SUPT3H | 0.08 | 0.09 | lasso | 3 | 0.08 | 6.4e-06 | 5.2 | -5.4 | 5.6e-08 | -0.83 | 0.09 | 0.90 | FALSE |
3 | GTEx | Nerve Tibial | SUPT3H | 0.17 | 0.12 | lasso | 5 | 0.10 | 2.2e-07 | 5.2 | -5.2 | 2.0e-07 | -0.84 | 0.11 | 0.89 | FALSE |
4 | GTEx | Pancreas | SUPT3H | 0.11 | 0.07 | lasso | 2 | 0.05 | 3.6e-03 | 5.5 | -5.5 | 3.2e-08 | -0.86 | 0.09 | 0.76 | FALSE |
5 | GTEx | Skin Sun Exposed Lower leg | SUPT3H | 0.07 | 0.03 | lasso | 5 | 0.04 | 4.2e-04 | 5.2 | -5.3 | 9.5e-08 | -0.81 | 0.10 | 0.80 | FALSE |
6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SUPT3H | 0.02 | 0.01 | blup | 191 | 0.01 | 3.0e-03 | 5.2 | -5.3 | 1.3e-07 | -0.79 | 0.11 | 0.87 | FALSE |
7 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SUPT3H | 0.04 | 0.01 | blup | 191 | 0.02 | 6.5e-03 | -3.3 | -5.3 | 1.1e-07 | -0.81 | 0.05 | 0.92 | FALSE |
8 | The Cancer Genome Atlas | Lung Adenocarcinoma | SUPT3H | 0.03 | 0.03 | lasso | 2 | 0.02 | 8.9e-04 | 5.4 | -5.5 | 3.7e-08 | -0.86 | 0.09 | 0.71 | FALSE |
9 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | SUPT3H | 0.12 | 0.08 | blup | 191 | 0.09 | 2.8e-04 | 5.2 | -5.4 | 6.3e-08 | -0.92 | 0.05 | 0.92 | FALSE |
10 | The Cancer Genome Atlas | Thyroid Carcinoma | SUPT3H | 0.06 | 0.04 | lasso | 4 | 0.05 | 2.1e-05 | 5.3 | -5.6 | 1.7e-08 | -0.83 | 0.08 | 0.89 | FALSE |