[Hub]/) : Traits : Arm fat-free mass (left) :

chr9:138,562,710-140,321,666

Best TWAS P=2.72e-10 · Best GWAS P=5.99e-08 conditioned to 0.356

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland INPP5E 0.18 0.02 enet 23 0.10 2.2e-04 4.7 -5.2 2.3e-07 -0.63 0.08 0.64 FALSE
2 GTEx Brain Caudate basal ganglia SNHG7 0.37 0.10 lasso 6 0.27 2.5e-08 -3.2 6.2 6.2e-10 0.34 0.08 0.57 TRUE
3 GTEx Brain Cerebellar Hemisphere INPP5E 0.25 0.23 enet 6 0.17 3.4e-05 4.7 -5.3 1.2e-07 -0.75 0.11 0.83 FALSE
4 GTEx Esophagus Muscularis SDCCAG3 0.10 0.02 enet 5 0.02 3.6e-02 3.3 -5.1 3.1e-07 -0.46 0.08 0.70 FALSE
5 GTEx Lung CARD9 0.08 0.04 enet 6 0.04 2.5e-04 5.4 5.3 1.5e-07 0.88 0.02 0.98 FALSE
6 GTEx Ovary INPP5E 0.24 0.13 enet 11 0.15 1.9e-04 5.0 -6.3 2.7e-10 -0.79 0.05 0.68 TRUE
7 GTEx Ovary SEC16A 0.33 0.06 enet 10 0.14 3.4e-04 4.6 -5.6 1.6e-08 -0.65 0.04 0.34 FALSE
8 GTEx Uterus INPP5E 0.60 0.04 enet 10 0.22 3.4e-05 5.3 -5.5 3.5e-08 -0.73 0.05 0.55 FALSE
9 GTEx Whole Blood SEC16A 0.07 0.05 lasso 5 0.04 1.3e-04 4.8 -5.4 6.7e-08 -0.62 0.10 0.89 FALSE
10 GTEx Whole Blood CARD9 0.08 0.07 lasso 1 0.05 4.2e-05 5.4 5.4 8.3e-08 0.98 0.02 0.98 FALSE
11 YFS Blood INPP5E 0.33 0.55 lasso 6 0.57 2.9e-235 5.3 -5.3 1.5e-07 -0.70 0.04 0.96 FALSE
12 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma INPP5E 0.25 0.10 lasso 3 0.09 4.9e-05 5.3 -5.5 4.0e-08 -0.70 0.01 0.96 FALSE
13 The Cancer Genome Atlas Colon Adenocarcinoma INPP5E 0.11 0.08 lasso 2 0.08 3.4e-05 5.3 -5.3 1.2e-07 -0.71 0.01 0.92 FALSE
14 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma INPP5E 0.07 0.04 blup 54 0.07 6.0e-05 5.4 -5.8 8.8e-09 -0.81 0.01 0.95 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SDCCAG3 0.05 0.01 blup 61 0.01 5.9e-02 5.1 -5.2 2.3e-07 -0.84 0.02 0.67 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma SEC16A 0.08 0.10 lasso 4 0.08 1.9e-08 5.4 -5.2 2.1e-07 -0.57 0.00 1.00 FALSE
17 The Cancer Genome Atlas Testicular Germ Cell Tumors INPP5E 0.10 0.06 blup 54 0.08 8.1e-04 4.7 -5.4 6.2e-08 -0.82 0.03 0.75 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma INPP5E 0.11 0.16 lasso 3 0.16 2.4e-15 5.1 -5.2 1.6e-07 -0.82 0.03 0.96 FALSE