TWAS
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Traits
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Traits
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Arm fat-free mass (left)
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chr1:106,906,072-108,296,508
Best TWAS P=7.68e-08 · Best GWAS P=2.18e-08 conditioned to 2.25e-09
107M
107.2M
107.4M
107.6M
107.8M
108M
108.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Muscle Skeletal
PRMT6
0.32
0.16
enet
13
0.16
2.8e-15
4.8
-5.4
7.7e-08
-0.07
0.25
0.75
TRUE
2
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
PRMT6
0.09
0.08
blup
36
0.08
3.3e-06
4.8
-5.3
1.3e-07
-0.08
0.01
0.98
FALSE