Best TWAS P=3.56e-09 · Best GWAS P=7.09e-08 conditioned to 0.0234
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | DCBLD2 | 0.14 | 0.12 | lasso | 5 | 0.15 | 1.5e-11 | -5.2 | 5.6 | 2.2e-08 | -0.83 | 0.01 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | DCBLD2 | 0.07 | 0.06 | enet | 3 | 0.07 | 7.6e-04 | -5.0 | 5.1 | 2.8e-07 | -0.98 | 0.01 | 0.89 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCBLD2 | 0.09 | 0.01 | enet | 16 | 0.04 | 9.6e-05 | 4.1 | 5.9 | 3.6e-09 | -0.61 | 0.03 | 0.85 | TRUE |