Best TWAS P=9.81e-08 · Best GWAS P=8.46e-09 conditioned to 0.000158
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | TRIM4 | 0.18 | 0.09 | enet | 17 | 0.13 | 1.8e-07 | 4.8 | -5.3 | 9.8e-08 | 0.45 | 0.17 | 0.82 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | TRIM4 | 0.39 | 0.26 | lasso | 11 | 0.25 | 5.5e-21 | 4.8 | -5.1 | 3.0e-07 | 0.45 | 0.16 | 0.83 | FALSE |
| 3 | GTEx | Whole Blood | TRIM4 | 0.12 | 0.05 | lasso | 5 | 0.06 | 5.9e-06 | 4.8 | -5.2 | 1.6e-07 | 0.47 | 0.13 | 0.86 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | TRIM4 | 0.22 | 0.28 | lasso | 10 | 0.29 | 5.5e-17 | 5.0 | -5.1 | 3.1e-07 | 0.46 | 0.09 | 0.90 | FALSE |