Best TWAS P=5.7e-19 · Best GWAS P=6.06e-21 conditioned to 0.000677
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | SLC38A2 | 0.02 | 0.02 | blup | 341 | 0.01 | 0.00581 | -8.7 | 7.9 | 3.5e-15 | -0.90 | 0.06 | 0.88 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC38A2 | 0.10 | 0.06 | blup | 30 | 0.05 | 0.00083 | -9.3 | 8.9 | 5.7e-19 | -0.86 | 0.01 | 0.91 | TRUE |
3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC38A2 | 0.06 | 0.01 | blup | 30 | 0.03 | 0.00513 | -9.3 | 7.9 | 2.0e-15 | -0.92 | 0.02 | 0.75 | FALSE |