Best TWAS P=2.38e-09 · Best GWAS P=1.14e-08 conditioned to 0.0285
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | DCBLD2 | 0.14 | 0.05 | lasso | 5 | 0.03 | 1.7e-03 | 4.1 | 5.1 | 3.0e-07 | 0.63 | 0.15 | 0.46 | FALSE |
2 | GTEx | Thyroid | DCBLD2 | 0.14 | 0.12 | lasso | 5 | 0.15 | 1.5e-11 | -5.0 | 5.4 | 8.0e-08 | 0.28 | 0.08 | 0.92 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCBLD2 | 0.09 | 0.01 | enet | 16 | 0.04 | 9.6e-05 | 4.3 | 6.0 | 2.4e-09 | 0.69 | 0.05 | 0.76 | TRUE |