Best TWAS P=3.03e-70 · Best GWAS P=5.87e-70 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZBTB38 | 0.08 | 0.04 | lasso | 4 | 0.03 | 8.1e-04 | 17.7 | 17.7 | 3.0e-70 | 0.98 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Colon Transverse | ACPL2 | 0.15 | -0.01 | lasso | 4 | 0.00 | 5.7e-01 | 5.6 | 5.6 | 2.1e-08 | 0.30 | 0.05 | 0.05 | TRUE |
| 3 | GTEx | Testis | ZBTB38 | 0.14 | 0.06 | lasso | 8 | 0.05 | 2.8e-03 | 10.6 | 12.0 | 2.1e-33 | 0.60 | 0.24 | 0.61 | FALSE |
| 4 | GTEx | Thyroid | ZBTB38 | 0.11 | 0.03 | enet | 32 | 0.04 | 2.9e-04 | 10.3 | 12.5 | 1.1e-35 | 0.62 | 0.07 | 0.92 | FALSE |
| 5 | NTR | Blood | ZBTB38 | 0.03 | 0.01 | lasso | 3 | 0.01 | 2.2e-05 | 17.6 | 15.2 | 6.3e-52 | 0.88 | 0.01 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZBTB38 | 0.04 | 0.03 | lasso | 3 | 0.04 | 3.0e-03 | 11.1 | 13.0 | 1.0e-38 | 0.59 | 0.04 | 0.42 | FALSE |