Best TWAS P=2.22e-08 · Best GWAS P=9.73e-07 conditioned to 0.216
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | UPF3A | 0.33 | 0.25 | enet | 19 | 0.29 | 6.2e-23 | -4.9 | -5.1 | 2.7e-07 | 0.90 | 0.00 | 0.99 | FALSE |
2 | GTEx | Breast Mammary Tissue | UPF3A | 0.33 | 0.06 | enet | 18 | 0.18 | 9.7e-10 | -3.8 | -5.6 | 2.2e-08 | 0.72 | 0.08 | 0.77 | TRUE |
3 | GTEx | Esophagus Muscularis | UPF3A | 0.43 | 0.25 | enet | 33 | 0.37 | 8.8e-24 | -4.9 | -5.4 | 8.0e-08 | 0.84 | 0.00 | 0.99 | FALSE |
4 | YFS | Blood | UPF3A | 0.21 | 0.17 | enet | 38 | 0.25 | 2.4e-82 | -4.9 | -5.2 | 1.8e-07 | 0.82 | 0.00 | 0.99 | FALSE |