Best TWAS P=2.98e-18 · Best GWAS P=4.93e-27 conditioned to 7.14e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | PPARG | 0.57 | 0.57 | lasso | 5 | 0.54 | 3.6e-16 | -6.1 | -6.1 | 1.1e-09 | -0.11 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Brain Cerebellum | PPARG | 0.64 | 0.57 | lasso | 7 | 0.57 | 4.1e-20 | -6.1 | -6.6 | 4.4e-11 | -0.12 | 1.00 | 0.00 | TRUE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | PPARG | 0.23 | 0.09 | lasso | 12 | 0.07 | 2.1e-03 | 2.9 | 5.1 | 3.0e-07 | 0.75 | 0.13 | 0.72 | TRUE |
| 4 | GTEx | Heart Left Ventricle | PPARG | 0.25 | 0.07 | enet | 36 | 0.10 | 5.1e-06 | 10.7 | 8.7 | 3.0e-18 | 0.69 | 0.01 | 0.98 | TRUE |