[Hub]/) : Traits : Trunk fat percentage :

chr10:130,566,749-132,263,732

Best TWAS P=6.6e-09 · Best GWAS P=2.93e-07 conditioned to 0.223

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland MGMT 0.39 0.25 lasso 6 0.30 1.5e-11 -4.8 5.1 2.7e-07 -0.77 0.02 0.97 FALSE
2 GTEx Brain Cerebellar Hemisphere MGMT 0.53 0.15 lasso 8 0.19 1.3e-05 -4.8 5.8 6.6e-09 -0.74 0.02 0.91 TRUE
3 GTEx Cells Transformed fibroblasts MGMT 0.45 0.30 enet 31 0.42 4.8e-34 -4.5 5.4 6.6e-08 -0.78 0.06 0.91 FALSE
4 GTEx Colon Transverse MGMT 0.47 0.24 enet 58 0.35 1.6e-17 -4.6 5.2 2.5e-07 -0.60 0.05 0.92 FALSE
5 GTEx Esophagus Mucosa MGMT 0.41 0.33 enet 37 0.38 2.3e-26 -4.6 5.2 2.5e-07 -0.65 0.04 0.94 FALSE
6 GTEx Heart Atrial Appendage MGMT 0.41 0.17 enet 33 0.22 4.6e-10 -4.6 5.4 5.6e-08 -0.77 0.03 0.96 FALSE
7 GTEx Prostate MGMT 0.25 0.13 lasso 4 0.20 9.4e-06 -4.8 5.5 4.0e-08 -0.83 0.03 0.90 FALSE
8 GTEx Skin Sun Exposed Lower leg MGMT 0.45 0.30 enet 42 0.46 1.6e-41 -4.5 5.3 9.1e-08 -0.73 0.04 0.94 FALSE
9 GTEx Stomach MGMT 0.33 0.20 enet 9 0.25 2.3e-12 -5.0 5.2 1.7e-07 -0.81 0.01 0.98 FALSE
10 ROSMAP Brain Pre-frontal Cortex MGMT 0.41 0.38 enet 46 0.48 3.6e-69 -4.6 5.2 1.9e-07 -0.74 0.03 0.96 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MGMT 0.10 0.09 enet 23 0.10 1.9e-11 -4.5 5.2 2.5e-07 -0.73 0.06 0.92 FALSE