Best TWAS P=2.35e-08 · Best GWAS P=6.06e-08 conditioned to 0.00301
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | REXO1 | 0.07 | 0.01 | bslmm | 391 | 0.01 | 0.0166 | -3.3 | 5.6 | 2.3e-08 | -0.51 | 0.06 | 0.74 | TRUE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ATP8B3 | 0.04 | 0.01 | blup | 49 | 0.02 | 0.0022 | -5.4 | -5.3 | 1.3e-07 | 0.84 | 0.00 | 0.69 | FALSE |