Best TWAS P=1.78e-08 · Best GWAS P=3.74e-11 conditioned to 0.000179
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | MED20 | 0.17 | 0.01 | enet | 10 | 0.06 | 6.0e-04 | 4.8 | 5.5 | 3.0e-08 | 0.69 | 0.17 | 0.62 | FALSE |
| 2 | GTEx | Lung | BYSL | 0.08 | 0.03 | lasso | 4 | 0.02 | 4.9e-03 | 5.8 | -5.3 | 1.4e-07 | -0.80 | 0.18 | 0.71 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | MED20 | 0.05 | 0.00 | blup | 50 | 0.04 | 2.8e-03 | 4.7 | 5.6 | 1.8e-08 | 0.70 | 0.06 | 0.29 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MED20 | 0.09 | 0.08 | enet | 12 | 0.09 | 5.5e-10 | 4.9 | 5.2 | 1.8e-07 | 0.62 | 0.98 | 0.02 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MED20 | 0.04 | 0.06 | enet | 6 | 0.05 | 2.6e-06 | 4.7 | 5.2 | 2.6e-07 | 0.58 | 0.88 | 0.04 | FALSE |