[Hub]/) : Traits : Trunk fat-free mass : ← →

chr18:11,968,117-13,822,256

Best TWAS P=1.04e-10 · Best GWAS P=2.57e-09 conditioned to 0.885

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
45	The Cancer Genome Atlas	Colon Adenocarcinoma	CEP192	0.06	0.05	blup	84	0.04	1.5e-03	5.7	6.5	1.0e-10	0.93	0.02	0.93	TRUE
53	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CEP192	0.12	0.06	blup	84	0.08	2.0e-04	4.6	6.1	9.5e-10	0.95	0.03	0.96	FALSE
51	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CEP192	0.11	0.16	lasso	3	0.16	7.6e-08	6.0	6.1	1.4e-09	0.99	0.02	0.98	FALSE
8	GTEx	Brain Cerebellar Hemisphere	CEP192	0.44	0.20	enet	22	0.26	2.2e-07	5.7	6.0	2.1e-09	0.93	0.03	0.97	FALSE
42	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CEP192	0.07	0.09	lasso	2	0.09	9.4e-08	6.0	6.0	2.7e-09	1.00	0.01	0.99	FALSE
21	GTEx	Esophagus Mucosa	SEH1L	0.09	0.02	enet	25	0.03	2.4e-03	-5.5	5.9	4.1e-09	0.47	0.05	0.86	FALSE
47	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SEH1L	0.03	0.01	blup	60	0.01	4.0e-02	-5.4	5.9	4.7e-09	0.70	0.02	0.45	FALSE
11	GTEx	Brain Frontal Cortex BA9	CEP192	0.27	0.19	lasso	11	0.18	1.3e-05	5.7	5.8	5.6e-09	0.93	0.03	0.96	FALSE
16	GTEx	Cells EBV-transformed lymphocytes	CEP192	0.52	0.34	lasso	5	0.36	1.6e-12	5.4	5.8	6.3e-09	0.90	0.03	0.97	FALSE
43	The Cancer Genome Atlas	Breast Invasive Carcinoma	CEP192	0.06	0.13	enet	9	0.13	3.4e-26	5.6	5.8	8.0e-09	0.97	0.03	0.97	FALSE
17	GTEx	Cells Transformed fibroblasts	SEH1L	0.10	0.03	enet	18	0.04	7.8e-04	5.7	5.7	9.4e-09	0.63	0.03	0.95	FALSE
13	GTEx	Breast Mammary Tissue	CEP192	0.38	0.40	lasso	4	0.42	4.7e-23	5.4	5.7	1.5e-08	0.96	0.03	0.97	FALSE
44	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CEP192	0.16	0.20	lasso	4	0.19	1.6e-09	5.6	5.6	1.7e-08	0.98	0.02	0.98	FALSE
54	The Cancer Genome Atlas	Prostate Adenocarcinoma	CEP192	0.33	0.49	lasso	5	0.49	1.0e-57	5.6	5.6	1.7e-08	0.98	0.02	0.98	FALSE
35	GTEx	Stomach	CEP192	0.37	0.44	lasso	5	0.43	1.5e-22	5.4	5.6	2.3e-08	0.96	0.05	0.95	FALSE
50	The Cancer Genome Atlas	Brain Lower Grade Glioma	SEH1L	0.05	0.00	blup	60	0.01	1.0e-02	5.4	5.6	2.3e-08	0.74	0.01	0.50	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CEP192	0.13	0.13	lasso	6	0.14	1.1e-16	5.6	5.6	2.4e-08	0.97	0.04	0.96	FALSE
36	GTEx	Thyroid	CEP192	0.37	0.48	lasso	7	0.52	3.2e-46	5.5	5.6	2.5e-08	0.97	0.04	0.96	FALSE
18	GTEx	Cells Transformed fibroblasts	CEP192	0.32	0.32	enet	39	0.39	2.7e-31	5.6	5.6	2.7e-08	0.93	0.03	0.97	FALSE
6	GTEx	Artery Tibial	CEP192	0.40	0.50	enet	29	0.54	7.3e-50	5.5	5.5	2.8e-08	0.97	0.04	0.96	FALSE
4	GTEx	Artery Aorta	CEP192	0.43	0.50	lasso	11	0.55	2.5e-35	5.5	5.5	2.9e-08	0.97	0.03	0.97	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	CEP192	0.38	0.39	lasso	4	0.39	4.7e-15	5.4	5.5	2.9e-08	0.97	0.03	0.97	FALSE
14	GTEx	Breast Mammary Tissue (Male)	CEP192	0.58	0.26	lasso	11	0.30	1.3e-07	5.5	5.5	3.1e-08	0.95	0.02	0.97	FALSE
29	GTEx	Ovary	CEP192	0.43	0.42	enet	25	0.43	6.5e-12	5.4	5.5	3.1e-08	0.97	0.02	0.98	FALSE
37	GTEx	Uterus	CEP192	0.52	0.43	lasso	6	0.41	1.7e-09	5.4	5.5	3.8e-08	0.96	0.03	0.97	FALSE
56	The Cancer Genome Atlas	Thyroid Carcinoma	CEP192	0.36	0.53	enet	19	0.54	2.6e-61	5.5	5.5	4.5e-08	0.98	0.02	0.98	FALSE
26	GTEx	Lung	CEP192	0.32	0.29	lasso	7	0.34	3.8e-27	5.4	5.5	4.7e-08	0.96	0.04	0.96	FALSE
33	GTEx	Skin Sun Exposed Lower leg	CEP192	0.34	0.36	lasso	3	0.38	3.5e-33	5.4	5.5	4.9e-08	0.97	0.08	0.92	FALSE
34	GTEx	Spleen	CEP192	0.54	0.52	lasso	5	0.49	2.8e-14	5.4	5.4	5.5e-08	0.97	0.04	0.96	FALSE
28	GTEx	Nerve Tibial	CEP192	0.44	0.52	lasso	12	0.55	3.1e-46	5.6	5.4	6.8e-08	0.97	0.03	0.97	FALSE
31	GTEx	Prostate	CEP192	0.57	0.59	enet	23	0.66	1.8e-21	5.5	5.4	7.5e-08	0.96	0.03	0.97	FALSE
2	GTEx	Adipose Subcutaneous	CEP192	0.38	0.44	enet	24	0.48	1.3e-44	5.4	5.4	7.7e-08	0.97	0.06	0.94	FALSE
5	GTEx	Artery Coronary	CEP192	0.32	0.35	lasso	5	0.33	8.2e-12	5.6	5.4	7.7e-08	0.97	0.03	0.97	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	SEH1L	0.18	0.13	lasso	4	0.08	1.3e-03	5.4	5.4	7.7e-08	0.93	0.04	0.73	FALSE
39	GTEx	Whole Blood	CEP192	0.17	0.16	enet	15	0.17	3.7e-15	5.4	5.4	8.0e-08	0.97	0.04	0.96	FALSE
10	GTEx	Brain Frontal Cortex BA9	SEH1L	0.29	-0.01	lasso	4	0.00	3.0e-01	5.7	5.4	8.1e-08	0.75	0.04	0.37	FALSE
46	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CEP192	0.21	0.31	lasso	4	0.31	1.0e-35	5.5	5.3	8.7e-08	0.97	0.04	0.96	FALSE
41	METSIM	Adipose	CEP76	0.04	0.00	bslmm	395	0.01	1.8e-02	2.5	5.3	9.3e-08	0.31	0.24	0.03	FALSE
12	GTEx	Brain Putamen basal ganglia	CEP192	0.50	0.39	lasso	5	0.36	2.4e-09	5.6	5.3	9.8e-08	0.95	0.03	0.97	FALSE
48	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CEP192	0.30	0.33	lasso	2	0.33	1.8e-19	5.4	5.3	9.9e-08	0.95	0.05	0.95	FALSE
22	GTEx	Esophagus Mucosa	CEP192	0.39	0.51	enet	29	0.52	7.4e-40	5.5	5.3	1.0e-07	0.97	0.03	0.97	FALSE
55	The Cancer Genome Atlas	Soft Tissue Sarcoma	CEP192	0.10	0.07	blup	84	0.08	1.2e-05	5.4	5.3	1.0e-07	0.96	0.03	0.96	FALSE
3	GTEx	Adrenal Gland	CEP192	0.44	0.56	lasso	2	0.56	9.6e-24	5.4	5.3	1.1e-07	0.96	0.07	0.93	FALSE
38	GTEx	Vagina	CEP192	0.51	0.31	lasso	4	0.37	2.3e-09	5.4	5.3	1.2e-07	0.94	0.03	0.97	FALSE
49	The Cancer Genome Atlas	Brain Lower Grade Glioma	CEP192	0.27	0.38	blup	84	0.38	1.5e-45	5.6	5.3	1.3e-07	0.95	0.04	0.96	FALSE
52	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CEP192	0.09	0.07	blup	84	0.09	2.1e-06	5.2	5.3	1.3e-07	0.92	0.04	0.96	FALSE
40	METSIM	Adipose	CEP192	0.19	0.32	lasso	5	0.32	1.0e-48	5.4	5.3	1.4e-07	0.96	0.05	0.95	FALSE
7	GTEx	Brain Caudate basal ganglia	CEP192	0.48	0.36	enet	19	0.36	4.2e-11	5.6	5.2	1.7e-07	0.96	0.03	0.97	FALSE
9	GTEx	Brain Cerebellum	CEP192	0.52	0.44	enet	31	0.52	5.6e-18	5.6	5.2	1.7e-07	0.92	0.03	0.97	FALSE
23	GTEx	Esophagus Muscularis	CEP192	0.39	0.46	lasso	9	0.52	2.1e-36	5.6	5.2	1.8e-07	0.97	0.04	0.96	FALSE
27	GTEx	Muscle Skeletal	CEP192	0.10	0.07	lasso	3	0.07	3.1e-07	5.4	5.2	1.8e-07	0.95	0.03	0.97	FALSE
19	GTEx	Colon Transverse	CEP192	0.45	0.54	lasso	8	0.57	1.2e-32	5.4	5.2	2.1e-07	0.96	0.05	0.95	FALSE
30	GTEx	Pituitary	SEH1L	0.22	0.07	lasso	6	0.05	2.1e-02	-5.5	5.2	2.2e-07	0.35	0.06	0.26	FALSE
24	GTEx	Heart Atrial Appendage	CEP192	0.29	0.28	lasso	5	0.26	4.3e-12	5.4	5.2	2.5e-07	0.95	0.02	0.98	FALSE
32	GTEx	Skin Not Sun Exposed Suprapubic	CEP192	0.34	0.35	enet	20	0.40	1.6e-23	5.6	5.1	2.7e-07	0.96	0.03	0.97	FALSE
25	GTEx	Heart Left Ventricle	CEP192	0.24	0.06	lasso	4	0.09	1.4e-05	5.4	5.1	3.0e-07	0.91	0.03	0.97	FALSE