Best TWAS P=1.47e-08 · Best GWAS P=5.48e-18 conditioned to 6.32e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | KCNJ15 | 0.05 | 0.03 | lasso | 5 | 0.02 | 6.8e-04 | -5.5 | 5.6 | 1.9e-08 | -0.65 | 0.82 | 0.12 | FALSE |
| 2 | NTR | Blood | KCNJ15 | 0.06 | 0.09 | lasso | 4 | 0.09 | 7.0e-27 | -5.3 | 5.4 | 7.5e-08 | -0.65 | 1.00 | 0.00 | FALSE |
| 3 | YFS | Blood | KCNJ15 | 0.22 | 0.29 | enet | 19 | 0.30 | 3.9e-100 | -5.5 | 5.5 | 4.6e-08 | -0.66 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | DSCR10 | 0.07 | 0.03 | blup | 35 | 0.06 | 3.0e-03 | 4.6 | -5.7 | 1.5e-08 | 0.67 | 0.02 | 0.65 | TRUE |