Hub : Traits :

Relative age of first facial hair

547 significantly associated models · 90 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 242723236 244359621 1 1 2.0e-08 8.0e-10 1.0e+00 100 SDCCAG8
2 2 66866767 68326904 2 1 1.3e-07 3.0e-10 3.1e-04 67 AC023115.4
3 2 222611837 224128542 2 2 2.2e-07 1.6e-13 3.0e-13 2 RP11-16P6.1 SGPP2
4 2 232718042 234145080 1 1 7.2e-08 4.8e-08 2.3e-01 95 EIF4E2
5 3 10617048 12457119 2 1 3.5e-10 4.2e-13 1.4e-04 72 VGLL4
6 3 48816725 52435860 14 11 1.2e-12 1.1e-10 NaN NaN HEMK1 HYAL3 RBM6 SEMA3B-AS1 TEX264
7 4 80561055 82578407 1 1 1.8e-07 5.8e-13 2.4e-11 14 C4orf22
8 4 94527983 95955095 1 1 1.3e-07 2.3e-08 1.0e+00 100 HPGDS
9 6 33856903 35362848 1 1 2.8e-08 4.3e-07 5.4e-01 98 C6orf106
10 6 41058968 42598371 3 5 1.3e-11 9.6e-11 1.0e+00 100 MED20 PRICKLE4
11 6 99192233 100719911 2 1 1.4e-10 1.2e-09 2.5e-08 16 RP1-199J3.5
12 6 104478130 106230491 2 1 3.3e-21 5.1e-35 1.8e-15 58 LIN28B
13 7 130101373 131880252 2 4 6.6e-24 4.7e-45 6.1e-08 85 MKLN1-AS2
14 10 17541614 19027696 1 1 1.3e-12 1.4e-09 4.3e-01 98 SLC39A12
15 10 64195778 65606229 1 1 6.8e-08 1.6e-07 2.9e-01 96 NRBF2
16 10 101975269 103362569 1 1 9.3e-08 1.3e-06 8.2e-01 100 RP11-179B2.2
17 11 29646947 31048683 1 1 2.3e-07 2.7e-05 1.2e-02 64 C11orf46
18 11 122058476 123525464 1 1 6.9e-15 5.7e-12 2.0e-02 89 C11orf63
19 12 64869118 66337026 1 1 4.8e-08 1.8e-09 9.0e-03 81 LEMD3
20 12 120502726 122037099 1 1 2.0e-08 3.9e-08 2.3e-01 95 SPPL3
21 14 24020127 25430242 1 1 3.7e-08 1.1e-09 3.0e-03 76 TGM1
22 15 27662957 28535266 1 1 7.8e-11 3.5e-33 6.3e-24 29 HERC2
23 16 13697975 15369019 2 1 9.3e-14 1.5e-36 1.6e-24 34 RP11-65J21.3
24 16 88858246 90172696 15 10 1.0e-17 2.0e-14 1.0e+00 100 AC092143.1 DBNDD1 GAS8 MC1R SPATA33 URAHP
25 17 42607368 46609918 24 2 2.6e-30 1.7e-28 1.0e+00 100 LRRC37A4P MRPL10
26 17 54272304 55667722 1 1 6.4e-13 8.5e-27 9.7e-16 44 MIR3614
27 20 32594714 34109427 1 1 3.3e-07 1.3e-06 4.8e-02 83 NCOA6
28 21 39849553 41383143 2 1 1.2e-08 1.8e-08 7.9e-02 90 PSMG1

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Verbal and Numeric Reasoning (VNR) 1.08 2 1 3.0 0.00 1.0e+00 LRRC37A4P RBM6
Breast Cancer 1.29 2 1 3.0 0.00 1.0e+00 AC092143.1 LRRC37A4P
Ovarian Cancer 1.33 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Age at First Birth 2.00 3 0 0.0 0.00 1.0e+00 DBNDD1 RBM6 RP11-179B2.2
HDL Cholesterol 1.25 2 1 3.0 0.00 1.0e+00 C6orf106 NCOA6
LDL Cholesterol 1.04 1 1 3.0 0.00 1.0e+00 C6orf106
Neuroticism 1.28 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Primary Biliary Cirrhosis 0.94 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Schizophrenia 1.87 3 0 0.0 0.00 1.0e+00 LIN28B SDCCAG8 SPATA33
Triglycerides 0.99 1 0 0.0 0.00 1.0e+00 NRBF2
Blood Eosinophil Count 1.97 6 5 15.2 -0.58 4.7e-02 HEMK1 LRRC37A4P RBM6 SEMA3B-AS1 SPPL3 TEX264
Blood Platelet Count 1.96 12 5 15.2 0.03 9.2e-01 AC023115.4 C6orf106 EIF4E2 HEMK1 HPGDS LRRC37A4P MED20 MRPL10 NRBF2 PSMG1 RP11-179B2.2 SPPL3
Blood Red Count 8.65 13 5 15.2 0.43 8.9e-02 AC092143.1 C4orf22 C6orf106 HEMK1 LRRC37A4P MC1R MED20 MRPL10 NRBF2 PRICKLE4 PSMG1 SEMA3B-AS1 URAHP
Blood White Count 1.31 7 5 15.2 0.37 4.2e-01 AC023115.4 LRRC37A4P MC1R NCOA6 NRBF2 RBM6 SLC39A12
Heel T-Score 1.55 7 6 18.2 0.83 1.1e-02 C11orf63 DBNDD1 LIN28B LRRC37A4P NCOA6 TGM1 VGLL4
BMI 1.83 11 8 24.2 0.37 1.9e-01 C11orf46 C4orf22 C6orf106 HEMK1 NCOA6 NRBF2 PSMG1 RBM6 RP11-179B2.2 SDCCAG8 TEX264
Height 4.49 23 21 63.6 -0.22 2.0e-01 C11orf63 C6orf106 DBNDD1 EIF4E2 GAS8 HEMK1 LEMD3 LIN28B LRRC37A4P MED20 MIR3614 MKLN1-AS2 NCOA6 NRBF2 PRICKLE4 RP11-179B2.2 RP11-65J21.3 SEMA3B-AS1 SPATA33 SPPL3 TEX264 TGM1 URAHP
Waist Hip Ratio (WHR) 1.92 8 4 12.1 -0.10 7.6e-01 C6orf106 HEMK1 LRRC37A4P MED20 NCOA6 PRICKLE4 TEX264 VGLL4
Systolic Blood Pressure 2.85 10 6 18.2 -0.40 1.8e-01 C11orf46 C4orf22 DBNDD1 LRRC37A4P MC1R MKLN1-AS2 NRBF2 SEMA3B-AS1 TEX264 VGLL4
Smoking Status 1.79 2 0 0.0 0.00 1.0e+00 C6orf106 DBNDD1
Allergy or Eczema 1.90 3 2 6.1 0.00 1.0e+00 C6orf106 PSMG1 SPPL3
Cardiovascular Disease 1.78 5 1 3.0 -0.31 6.1e-01 C11orf46 C4orf22 NRBF2 SPATA33 VGLL4
Respiratory disease 2.06 5 0 0.0 0.38 5.3e-01 DBNDD1 PSMG1 RBM6 SPATA33 URAHP
Lung FEV1/FVC ratio 1.17 7 3 9.1 0.10 8.4e-01 C6orf106 HEMK1 LRRC37A4P NCOA6 NRBF2 PSMG1 VGLL4
Lung FVC 2.55 9 7 21.2 0.85 1.9e-03 C6orf106 EIF4E2 HEMK1 LIN28B LRRC37A4P NCOA6 SEMA3B-AS1 SPPL3 TEX264
Neuroticism 2.03 3 1 3.0 0.00 1.0e+00 HEMK1 LIN28B LRRC37A4P
Chronotype (morning person) 2.57 4 3 9.1 0.01 9.7e-01 HEMK1 MED20 PRICKLE4 SEMA3B-AS1
Hair Pigment 170.95 17 12 36.4 -0.73 1.5e-04 AC092143.1 C4orf22 C6orf106 DBNDD1 GAS8 HERC2 LRRC37A4P MC1R MED20 MIR3614 MRPL10 NCOA6 SGPP2 SLC39A12 SPATA33 URAHP VGLL4
Tanning 137.27 9 8 24.2 0.82 1.5e-04 AC092143.1 DBNDD1 GAS8 HERC2 MC1R MED20 NCOA6 SPATA33 URAHP
Hand grip strength (left) 1.70 3 2 6.1 0.00 1.0e+00 LIN28B LRRC37A4P NCOA6
Number of treatments/medications taken 1.93 1 0 0.0 0.00 1.0e+00 LIN28B
Sensitivity / hurt feelings 2.00 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Hearing difficulty/problems: Yes 1.82 1 0 0.0 0.00 1.0e+00 SDCCAG8
Other serious medical condition/disability diagnosed by doctor 1.41 1 0 0.0 0.00 1.0e+00 PRICKLE4
Systolic blood pressure, automated reading 2.23 4 3 9.1 -0.04 9.5e-01 C4orf22 LRRC37A4P MKLN1-AS2 VGLL4
Vitamin and mineral supplements 1.86 1 0 0.0 0.00 1.0e+00 NRBF2
Impedance of leg (right) 3.44 11 7 21.2 0.27 2.8e-01 C6orf106 DBNDD1 HEMK1 LIN28B LRRC37A4P MED20 NCOA6 RBM6 RP11-179B2.2 SEMA3B-AS1 TEX264
Leg fat-free mass (left) 3.14 11 6 18.2 0.25 4.2e-01 C6orf106 DBNDD1 LEMD3 LIN28B MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 SPPL3 TGM1
Trunk fat percentage 2.45 9 4 12.1 -0.63 3.0e-02 AC092143.1 C11orf63 C6orf106 DBNDD1 GAS8 LRRC37A4P MC1R PSMG1 URAHP
Hand grip strength (right) 2.01 4 2 6.1 -0.32 6.8e-01 C6orf106 LIN28B LRRC37A4P NCOA6
Fed-up feelings 0.95 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Frequency of unenthusiasm / disinterest in last 2 weeks 1.58 1 0 0.0 0.00 1.0e+00 HEMK1
Relative age voice broke 10.07 15 6 18.2 0.98 5.1e-14 C11orf63 DBNDD1 HEMK1 HPGDS LIN28B LRRC37A4P MED20 MKLN1-AS2 NCOA6 PRICKLE4 PSMG1 RP11-65J21.3 RP1-199J3.5 SPPL3 TEX264
Taking other prescription medications 2.98 2 0 0.0 0.00 1.0e+00 HEMK1 RBM6
Age when periods started (menarche) 9.14 16 10 30.3 0.94 6.9e-12 C11orf63 C6orf106 HEMK1 HPGDS HYAL3 LIN28B LRRC37A4P MED20 NRBF2 PRICKLE4 PSMG1 RBM6 RP11-179B2.2 RP11-65J21.3 SEMA3B-AS1 TEX264
Heel bone mineral density (BMD) T-score, automated (left) 1.38 3 0 0.0 0.00 1.0e+00 LIN28B LRRC37A4P NCOA6
High blood pressure 2.31 6 2 6.1 0.38 4.1e-01 C4orf22 DBNDD1 GAS8 MC1R NRBF2 SPATA33
Hayfever, allergic rhinitis or eczema 1.98 3 1 3.0 0.32 5.4e-01 C6orf106 SPPL3 TEX264
Multivitamins +/- minerals 1.75 2 1 3.0 0.00 1.0e+00 NCOA6 NRBF2
Supplements: Glucosamine 1.57 1 0 0.0 0.00 1.0e+00 NRBF2
Medication: Atenolol 2.27 2 0 0.0 0.00 1.0e+00 C4orf22 DBNDD1
Sitting height 3.07 14 9 27.3 -0.02 9.4e-01 C6orf106 DBNDD1 EIF4E2 HEMK1 LEMD3 LRRC37A4P MED20 NCOA6 PRICKLE4 RP11-179B2.2 RP11-65J21.3 TEX264 URAHP VGLL4
High blood pressure (mother) 1.42 1 0 0.0 0.00 1.0e+00 C4orf22
Body mass index (BMI) 1.79 8 5 15.2 -0.54 7.1e-02 C6orf106 HEMK1 NCOA6 NRBF2 PSMG1 RBM6 RP11-179B2.2 TEX264
Impedance of leg (left) 3.43 12 7 21.2 0.19 4.3e-01 C6orf106 DBNDD1 HEMK1 LIN28B LRRC37A4P MC1R MED20 NCOA6 RBM6 RP11-179B2.2 SEMA3B-AS1 TEX264
Leg predicted mass (left) 3.15 11 6 18.2 0.25 4.2e-01 C6orf106 DBNDD1 LEMD3 LIN28B MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 SPPL3 TGM1
Trunk fat mass 2.86 13 4 12.1 -0.14 5.7e-01 C11orf63 C6orf106 DBNDD1 EIF4E2 LIN28B LRRC37A4P MC1R MED20 NCOA6 PSMG1 RBM6 RP11-179B2.2 URAHP
Waist circumference 1.73 5 1 3.0 -0.20 6.7e-01 C6orf106 DBNDD1 NCOA6 RBM6 RP11-179B2.2
Past tobacco smoking 1.70 1 0 0.0 0.00 1.0e+00 NCOA6
Alcohol usually taken with meals 1.27 2 0 0.0 0.00 1.0e+00 NRBF2 PRICKLE4
Nervous feelings 1.47 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Frequency of tenseness / restlessness in last 2 weeks 1.50 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Hearing difficulty/problems with background noise 1.46 3 0 0.0 0.00 1.0e+00 LIN28B LRRC37A4P VGLL4
Hair/balding pattern: Pattern 2 2.58 3 2 6.1 0.00 1.0e+00 C4orf22 LRRC37A4P SGPP2
Had menopause 3.67 2 0 0.0 0.00 1.0e+00 DBNDD1 MC1R
Had other major operations 1.68 1 0 0.0 0.00 1.0e+00 RBM6
Forced vital capacity (FVC) 1.83 6 3 9.1 -0.39 3.9e-01 C6orf106 DBNDD1 LEMD3 LRRC37A4P RP11-179B2.2 RP11-65J21.3
Heel bone mineral density (BMD) T-score, automated (right) 1.50 3 0 0.0 0.00 1.0e+00 DBNDD1 LRRC37A4P NCOA6
Ever unenthusiastic/disinterested for a whole week 2.21 2 0 0.0 0.00 1.0e+00 HEMK1 LRRC37A4P
Heart attack 0.92 1 0 0.0 0.00 1.0e+00 C6orf106
Allergy 2.17 4 0 0.0 -0.59 4.1e-01 C6orf106 PSMG1 SEMA3B-AS1 SPPL3
Hayfever/allergic rhinitis (self-reported) 2.11 1 0 0.0 0.00 1.0e+00 TEX264
Fluid intelligence score 0.77 1 0 0.0 0.00 1.0e+00 RBM6
Neuroticism score 1.70 2 1 3.0 0.00 1.0e+00 HEMK1 LRRC37A4P
Weight 3.05 11 6 18.2 0.10 7.0e-01 C11orf63 C6orf106 DBNDD1 EIF4E2 MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 TGM1 URAHP
Impedance of arm (right) 3.15 12 9 27.3 0.26 3.3e-01 DBNDD1 HEMK1 HYAL3 LIN28B LRRC37A4P NCOA6 NRBF2 PSMG1 RBM6 RP11-179B2.2 TEX264 URAHP
Arm fat percentage (right) 1.45 4 1 3.0 -0.03 9.7e-01 C6orf106 DBNDD1 PSMG1 RBM6
Trunk fat-free mass 3.30 14 7 21.2 0.36 1.7e-01 C6orf106 DBNDD1 EIF4E2 HYAL3 LEMD3 LIN28B MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 RP11-65J21.3 SPPL3 TGM1
Hip circumference 2.68 9 4 12.1 0.02 9.6e-01 C6orf106 DBNDD1 MED20 NCOA6 PRICKLE4 PSMG1 RBM6 RP11-179B2.2 URAHP
Worrier / anxious feelings 0.72 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Frequency of tiredness / lethargy in last 2 weeks 1.68 1 0 0.0 0.00 1.0e+00 NCOA6
Hair/balding pattern: Pattern 3 3.47 3 2 6.1 0.00 1.0e+00 C4orf22 LRRC37A4P MIR3614
Number of live births 1.91 2 0 0.0 0.00 1.0e+00 DBNDD1 LRRC37A4P
Forced expiratory volume in 1-second (FEV1) 1.92 5 3 9.1 -0.04 9.5e-01 C6orf106 LEMD3 LRRC37A4P RP11-179B2.2 RP11-65J21.3
Pulse rate 1.62 1 0 0.0 0.00 1.0e+00 MKLN1-AS2
Qualifications: A levels/AS levels or equivalent 1.10 2 1 3.0 0.00 1.0e+00 LRRC37A4P RBM6
Asthma 1.97 3 0 0.0 0.00 1.0e+00 SPATA33 SPPL3 URAHP
Forced expiratory volume in 1-second (FEV1), Best measure 1.70 4 1 3.0 -0.04 9.6e-01 C6orf106 LEMD3 LRRC37A4P RP11-65J21.3
Impedance of arm (left) 3.26 12 9 27.3 0.15 5.7e-01 AC092143.1 DBNDD1 HEMK1 HYAL3 LIN28B LRRC37A4P MC1R NCOA6 NRBF2 RBM6 RP11-179B2.2 TEX264
Arm fat mass (right) 2.02 7 4 12.1 0.05 9.1e-01 C6orf106 DBNDD1 MED20 NCOA6 PSMG1 RBM6 RP11-179B2.2
Trunk predicted mass 3.30 13 7 21.2 0.43 1.1e-01 C6orf106 EIF4E2 HYAL3 LEMD3 LIN28B MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 RP11-65J21.3 SPPL3 TGM1
Standing height 4.24 20 19 57.6 0.32 8.4e-02 C11orf63 C6orf106 DBNDD1 EIF4E2 GAS8 HEMK1 LEMD3 LIN28B LRRC37A4P MED20 NCOA6 NRBF2 PRICKLE4 RP11-179B2.2 RP11-65J21.3 SEMA3B-AS1 SPPL3 TEX264 TGM1 URAHP
Breastfed as a baby 1.18 1 0 0.0 0.00 1.0e+00 NCOA6
Hair/balding pattern: Pattern 4 6.03 11 4 12.1 -0.45 9.1e-02 AC023115.4 C4orf22 DBNDD1 GAS8 LRRC37A4P MIR3614 MKLN1-AS2 NCOA6 SPATA33 URAHP VGLL4
Peak expiratory flow (PEF) 2.01 3 2 6.1 0.00 1.0e+00 LRRC37A4P NCOA6 RP11-65J21.3
Ever highly irritable/argumentative for 2 days 1.89 2 0 0.0 0.00 1.0e+00 HEMK1 RBM6
Qualifications: O levels/GCSEs or equivalent 1.21 1 0 0.0 0.00 1.0e+00 PSMG1
Medication: Paracetamol 1.64 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Headache pain in last month 0.99 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Medication for cholesterol, blood pressure or diabetes 1.29 1 0 0.0 0.00 1.0e+00 C4orf22
Chronic bronchitis/emphysema (mother) 2.15 1 0 0.0 0.00 1.0e+00 DBNDD1
Forced vital capacity (FVC), Best measure 1.73 5 3 9.1 -0.11 8.6e-01 C6orf106 LEMD3 LRRC37A4P RP11-179B2.2 RP11-65J21.3
Body fat percentage 1.88 6 2 6.1 -0.52 1.5e-01 C11orf63 C6orf106 DBNDD1 LRRC37A4P MC1R PSMG1
Leg fat percentage (right) 1.27 4 1 3.0 0.42 5.8e-01 C6orf106 NRBF2 PSMG1 RBM6
Arm fat-free mass (right) 3.23 11 8 24.2 0.42 1.5e-01 C6orf106 EIF4E2 HYAL3 LEMD3 MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 RP11-65J21.3 TGM1
Comparative body size at age 10 2.16 5 2 6.1 -0.99 1.4e-03 AC023115.4 HEMK1 LIN28B SPPL3 VGLL4
Worry too long after embarrassment 2.21 4 2 6.1 0.99 1.6e-03 DBNDD1 GAS8 LRRC37A4P URAHP
Wheeze or whistling in the chest in last year 2.16 2 1 3.0 0.00 1.0e+00 RBM6 SPATA33
Age at first live birth 1.59 1 1 3.0 0.00 1.0e+00 RBM6
Qualifications: College or University degree 1.30 3 2 6.1 0.00 1.0e+00 HPGDS LRRC37A4P RBM6
Medication for pain relief, constipation, heartburn 1.48 2 0 0.0 0.00 1.0e+00 C6orf106 LRRC37A4P
Neck or shoulder pain in last month 1.79 1 0 0.0 0.00 1.0e+00 MC1R
Medication: Blood pressure 1.63 1 1 3.0 0.00 1.0e+00 C4orf22
Angina (self-reported) 1.82 1 0 0.0 0.00 1.0e+00 NCOA6
Whole body fat mass 2.37 10 4 12.1 -0.06 8.3e-01 C11orf63 C6orf106 DBNDD1 EIF4E2 MED20 NCOA6 PSMG1 RBM6 RP11-179B2.2 URAHP
Leg fat mass (right) 1.96 6 3 9.1 -0.20 6.7e-01 C6orf106 DBNDD1 NCOA6 PSMG1 RBM6 RP11-179B2.2
Arm predicted mass (right) 3.13 10 8 24.2 0.48 1.1e-01 C6orf106 EIF4E2 HYAL3 LEMD3 MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 RP11-65J21.3
Pulse rate, automated reading 2.41 8 3 9.1 -0.77 1.2e-03 C4orf22 C6orf106 EIF4E2 MED20 MKLN1-AS2 PRICKLE4 PSMG1 RP1-199J3.5
Alcohol intake frequency. 1.05 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Comparative height size at age 10 2.29 7 6 18.2 -0.40 3.8e-01 C6orf106 EIF4E2 LRRC37A4P NCOA6 RP11-179B2.2 RP1-199J3.5 TGM1
Suffer from 'nerves' 0.89 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Overall health rating 1.48 2 0 0.0 0.00 1.0e+00 C6orf106 HEMK1
Chest pain or discomfort 1.91 1 0 0.0 0.00 1.0e+00 RBM6
Age at last live birth 1.66 2 1 3.0 0.00 1.0e+00 NRBF2 RBM6
Supplements: Vitamin C 1.51 1 0 0.0 0.00 1.0e+00 PRICKLE4
Knee pain experienced in last month 1.25 1 0 0.0 0.00 1.0e+00 RBM6
Hypertension (Self-reported) 2.18 4 2 6.1 0.11 8.9e-01 C4orf22 DBNDD1 NRBF2 SPATA33
Forced expiratory volume in 1-second (FEV1), predicted 4.38 7 4 12.1 0.36 3.4e-01 C6orf106 DBNDD1 HEMK1 LEMD3 LIN28B NCOA6 SEMA3B-AS1
Whole body fat-free mass 3.30 14 7 21.2 0.36 1.7e-01 C6orf106 DBNDD1 EIF4E2 HYAL3 LEMD3 LIN28B MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 RP11-65J21.3 SPPL3 TGM1
Leg fat-free mass (right) 3.08 9 6 18.2 0.33 3.2e-01 C6orf106 LEMD3 LIN28B MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 TGM1
Arm fat percentage (left) 1.48 3 1 3.0 0.00 1.0e+00 C6orf106 PSMG1 RBM6
Handedness (chirality/laterality): Left-handed 1.55 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Mood swings 1.80 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Loneliness, isolation 1.42 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Ever had bowel cancer screening 1.98 1 1 3.0 0.00 1.0e+00 PRICKLE4
Friendships satisfaction 1.29 1 0 0.0 0.00 1.0e+00 RP11-65J21.3
Mouth/teeth dental problems: Mouth ulcers 1.44 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Medication for cholesterol 2.11 2 1 3.0 0.00 1.0e+00 C4orf22 MC1R
Back pain experienced in last month 1.34 1 0 0.0 0.00 1.0e+00 C6orf106
Mineral and other dietary supplements 2.45 3 1 3.0 0.52 4.8e-01 MED20 NRBF2 PRICKLE4
Asthma (self-reported) 1.95 2 0 0.0 0.00 1.0e+00 SPATA33 URAHP
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.67 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Whole body water mass 3.32 14 7 21.2 0.36 1.7e-01 C6orf106 DBNDD1 EIF4E2 HYAL3 LEMD3 LIN28B MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 RP11-65J21.3 SPPL3 TGM1
Leg predicted mass (right) 3.09 9 6 18.2 0.33 3.3e-01 C6orf106 LEMD3 LIN28B MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 TGM1
Arm fat mass (left) 2.10 7 3 9.1 0.05 9.0e-01 C6orf106 DBNDD1 MED20 NCOA6 PSMG1 RBM6 RP11-179B2.2
Average weekly champagne plus white wine intake 1.18 1 0 0.0 0.00 1.0e+00 LRRC37A4P
Miserableness 2.10 2 1 3.0 0.00 1.0e+00 DBNDD1 LRRC37A4P
Guilty feelings 1.41 2 1 3.0 0.00 1.0e+00 LIN28B LRRC37A4P
Commuting to job workplace: Public transport 1.60 1 0 0.0 0.00 1.0e+00 SEMA3B-AS1
Medication: Blood pressure 2.40 5 2 6.1 -0.18 7.7e-01 C4orf22 LRRC37A4P MC1R NRBF2 SPATA33
Supplements: Fish oil (including cod liver oil) 1.63 1 0 0.0 0.00 1.0e+00 NRBF2
Medication: Paracetamol 1.44 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Illnesses of father: High blood pressure 2.02 1 0 0.0 0.00 1.0e+00 C4orf22
Basal metabolic rate 3.37 13 7 21.2 0.30 2.7e-01 C6orf106 DBNDD1 EIF4E2 LEMD3 LIN28B MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 RP11-65J21.3 SPPL3 TGM1
Leg fat percentage (left) 1.30 4 2 6.1 0.43 5.7e-01 C6orf106 NRBF2 PSMG1 RBM6
Arm fat-free mass (left) 3.26 11 6 18.2 0.40 1.8e-01 C6orf106 EIF4E2 HYAL3 LEMD3 MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 RP11-65J21.3 TGM1
Number of operations (self-reported) 2.01 1 0 0.0 0.00 1.0e+00 LIN28B
Average weekly beer plus cider intake 2.52 3 0 0.0 0.63 3.7e-01 NRBF2 PRICKLE4 PSMG1
Irritability 1.17 1 1 3.0 0.00 1.0e+00 LRRC37A4P
Risk taking 1.75 1 1 3.0 0.00 1.0e+00 SDCCAG8
Diastolic blood pressure, automated reading 1.51 2 2 6.1 0.00 1.0e+00 C4orf22 NRBF2
Ever depressed for a whole week 2.14 2 0 0.0 0.00 1.0e+00 HEMK1 SDCCAG8
Myopia 0.86 1 0 0.0 0.00 1.0e+00 C6orf106
Vascular/heart problems diagnosed by doctor 2.20 6 1 3.0 -0.38 4.6e-01 C4orf22 DBNDD1 GAS8 MC1R NRBF2 SPATA33
Medication: Omeprazole (e.g. Zanprol) 2.41 2 0 0.0 -1.00 1.6e-04 MED20 PRICKLE4
Pain experienced in last month 1.36 1 0 0.0 0.00 1.0e+00 C6orf106
Basal cell carcinoma (self-reported) 7.31 5 4 12.1 0.97 2.5e-05 DBNDD1 GAS8 MC1R SPATA33 URAHP
Heart attack/myocardial infarction (self-reported) 0.94 1 0 0.0 0.00 1.0e+00 C6orf106
Impedance of whole body 3.67 15 9 27.3 0.16 5.0e-01 AC092143.1 DBNDD1 HEMK1 HYAL3 LIN28B LRRC37A4P MC1R MED20 NCOA6 NRBF2 RBM6 RP11-179B2.2 SEMA3B-AS1 TEX264 URAHP
Leg fat mass (left) 1.99 6 3 9.1 -0.19 6.9e-01 C6orf106 DBNDD1 NCOA6 PSMG1 RBM6 RP11-179B2.2
Arm predicted mass (left) 3.24 11 7 21.2 0.40 1.8e-01 C6orf106 EIF4E2 HYAL3 LEMD3 MED20 NCOA6 PRICKLE4 RBM6 RP11-179B2.2 RP11-65J21.3 TGM1

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 17 0.487 2.16
GTEx Adipose Visceral Omentum 11 0.540 2.28
GTEx Adrenal Gland 8 0.549 2.16
GTEx Artery Aorta 13 0.437 2.13
GTEx Artery Coronary 11 0.930 2.70
GTEx Artery Tibial 14 0.372 1.97
GTEx Brain Caudate basal ganglia 6 0.652 2.30
GTEx Brain Cerebellar Hemisphere 9 0.604 2.28
GTEx Brain Cerebellum 11 0.555 2.18
GTEx Brain Cortex 10 0.966 2.72
GTEx Brain Frontal Cortex BA9 6 0.649 2.53
GTEx Brain Hippocampus 5 0.954 2.87
GTEx Brain Hypothalamus 8 1.356 2.88
GTEx Brain Nucleus accumbens basal ganglia 7 0.809 2.66
GTEx Brain Putamen basal ganglia 6 0.962 2.71
GTEx Breast Mammary Tissue 9 0.456 2.29
GTEx Breast Mammary Tissue (Male) 10 0.838 2.53
GTEx Breast Mammary Tissue (Female) 12 0.730 2.37
GTEx Cells EBV-transformed lymphocytes 12 0.843 2.52
GTEx Cells Transformed fibroblasts 14 0.333 2.07
GTEx Colon Sigmoid 10 0.684 2.44
GTEx Colon Transverse 13 0.630 2.39
GTEx Esophagus Gastroesophageal Junction 11 0.761 2.56
GTEx Esophagus Mucosa 15 0.452 2.09
GTEx Esophagus Muscularis 13 0.402 2.22
GTEx Heart Atrial Appendage 11 0.697 2.39
GTEx Heart Left Ventricle 12 0.784 2.36
GTEx Liver 6 0.837 2.37
GTEx Lung 15 0.522 2.20
GTEx Muscle Skeletal 14 0.484 2.12
GTEx Nerve Tibial 19 0.440 2.05
GTEx Ovary 8 0.881 2.74
GTEx Pancreas 12 0.735 2.30
GTEx Pituitary 5 0.448 2.28
GTEx Prostate 6 0.719 2.45
GTEx Skin Not Sun Exposed Suprapubic 13 0.529 2.25
GTEx Skin Sun Exposed Lower leg 11 0.302 2.07
GTEx Small Intestine Terminal Ileum 6 1.302 2.91
GTEx Spleen 10 0.709 2.21
GTEx Stomach 14 0.963 2.53
GTEx Testis 20 0.634 2.22
GTEx Thyroid 17 0.425 2.19
GTEx Uterus 6 1.058 2.97
GTEx Vagina 5 0.787 2.58
GTEx Whole Blood 9 0.452 2.14
METSIM Adipose 7 0.152 1.72
NTR Blood 5 0.208 1.82
ROSMAP Brain Pre-frontal Cortex 6 0.137 1.76
YFS Blood 5 0.108 1.67
CommonMind Brain Pre-frontal Cortex 17 0.316 1.79
TCGA Breast Tumor 3 0.391 1.98
TCGA Breast Normal 6 0.143 1.69
TCGA Ovarian Tumor 10 0.342 1.91
TCGA Prostate Tumor 8 0.231 1.80