[Hub]/) : Traits : Diabetes diagnosed by doctor : ← →

chr4:5,575,751-7,002,344

Best TWAS P=4.95e-17 · Best GWAS P=8.77e-18 conditioned to 0.000285

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex WFS1 0.10 0.03 lasso 2 0.02 4.8e-04 -8.1 8.1 4.7e-16 -0.73 0.06 0.90 FALSE
2 GTEx Brain Cerebellar Hemisphere WFS1 0.72 0.49 lasso 13 0.47 1.3e-13 -8.0 8.0 1.1e-15 -0.73 0.05 0.95 FALSE
3 GTEx Brain Cerebellum WFS1 0.44 0.26 lasso 10 0.27 9.8e-09 -8.0 8.0 1.0e-15 -0.73 0.06 0.94 FALSE
4 GTEx Cells Transformed fibroblasts WFS1 0.22 0.04 enet 25 0.08 2.6e-06 -7.9 8.1 4.8e-16 -0.77 0.04 0.95 FALSE
5 GTEx Muscle Skeletal WFS1 0.13 0.11 lasso 5 0.09 3.9e-09 -7.9 7.7 1.3e-14 -0.67 0.34 0.66 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic WFS1 0.35 0.25 lasso 7 0.28 7.6e-16 -7.9 7.7 1.4e-14 -0.62 0.05 0.95 FALSE
7 GTEx Skin Sun Exposed Lower leg WFS1 0.29 0.29 lasso 3 0.29 2.6e-24 -8.0 8.0 1.4e-15 -0.73 0.18 0.82 FALSE
8 GTEx Testis WFS1 0.38 0.05 lasso 7 0.01 7.0e-02 -7.9 6.0 2.2e-09 -0.29 0.22 0.38 FALSE
9 GTEx Thyroid WFS1 0.19 0.12 lasso 4 0.10 2.9e-08 -8.0 8.0 1.7e-15 -0.73 0.16 0.84 FALSE
10 METSIM Adipose WFS1 0.06 0.01 enet 14 0.02 1.5e-04 -8.1 6.8 7.5e-12 -0.72 0.02 0.97 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma WFS1 0.07 0.10 lasso 3 0.10 2.6e-11 -8.1 8.4 4.9e-17 -0.73 0.04 0.96 TRUE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma WFS1 0.04 0.00 blup 76 0.01 4.0e-02 -2.8 6.8 1.0e-11 -0.67 0.04 0.38 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma WFS1 0.04 0.01 blup 76 0.01 1.6e-02 -7.6 8.0 1.5e-15 -0.78 0.04 0.93 FALSE