TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr5:130,936,652-132,401,730
Best TWAS P=5.69e-08 · Best GWAS P=2.06e-06 conditioned to 0.0226
131M
131.2M
131.4M
131.6M
131.8M
132M
132.2M
132.4M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Whole Blood
SLC22A4
0.07
0.05
enet
16
0.05
4.6e-05
-4.5
-5.4
5.7e-08
0.51
0.02
0.86
TRUE
2
GTEx
Whole Blood
AC034220.3
0.08
0.05
enet
31
0.06
4.0e-06
3.6
-5.2
2.0e-07
0.51
0.08
0.73
FALSE