Best TWAS P=5.65e-13 · Best GWAS P=1.68e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CEP68 | 0.15 | 0.11 | lasso | 4 | 0.12 | 6.7e-10 | -6.9 | 7.0 | 2.0e-12 | -0.95 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Artery Aorta | CEP68 | 0.10 | 0.15 | lasso | 5 | 0.14 | 3.4e-08 | -7.1 | 7.0 | 1.9e-12 | -1.00 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Coronary | CEP68 | 0.20 | 0.04 | lasso | 7 | 0.03 | 3.6e-02 | -7.1 | 6.8 | 1.2e-11 | -0.98 | 0.01 | 0.95 | FALSE |
| 4 | GTEx | Artery Tibial | CEP68 | 0.24 | 0.19 | lasso | 5 | 0.20 | 1.8e-15 | -6.9 | 7.2 | 5.7e-13 | -0.98 | 0.00 | 1.00 | TRUE |
| 5 | GTEx | Cells Transformed fibroblasts | CEP68 | 0.17 | 0.14 | lasso | 3 | 0.12 | 1.9e-09 | -7.1 | 7.1 | 1.6e-12 | -1.00 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Esophagus Gastroesophageal Junction | CEP68 | 0.25 | 0.01 | lasso | 4 | 0.08 | 8.6e-04 | -6.1 | 5.3 | 1.5e-07 | -0.76 | 0.02 | 0.83 | FALSE |
| 7 | GTEx | Esophagus Muscularis | CEP68 | 0.16 | 0.13 | enet | 7 | 0.17 | 2.2e-10 | -6.9 | 7.0 | 2.7e-12 | -0.93 | 0.01 | 0.99 | FALSE |
| 8 | GTEx | Heart Atrial Appendage | CEP68 | 0.26 | 0.20 | lasso | 3 | 0.19 | 4.6e-09 | -7.1 | 6.9 | 4.7e-12 | -0.99 | 0.00 | 1.00 | FALSE |
| 9 | GTEx | Heart Left Ventricle | CEP68 | 0.14 | 0.05 | lasso | 7 | 0.05 | 1.7e-03 | -6.9 | 7.1 | 1.5e-12 | -0.95 | 0.00 | 0.99 | FALSE |
| 10 | GTEx | Lung | CEP68 | 0.12 | 0.13 | lasso | 3 | 0.12 | 1.6e-09 | -6.9 | 6.7 | 1.7e-11 | -0.95 | 0.00 | 1.00 | FALSE |
| 11 | GTEx | Muscle Skeletal | CEP68 | 0.13 | 0.07 | lasso | 7 | 0.07 | 2.1e-07 | -6.9 | 6.4 | 1.4e-10 | -0.93 | 0.01 | 0.99 | FALSE |
| 12 | GTEx | Ovary | CEP68 | 0.38 | 0.26 | lasso | 7 | 0.24 | 1.6e-06 | -6.9 | 6.9 | 3.8e-12 | -0.96 | 0.00 | 0.99 | FALSE |
| 13 | GTEx | Pancreas | CEP68 | 0.28 | 0.11 | lasso | 6 | 0.13 | 5.6e-06 | -6.9 | 6.3 | 2.2e-10 | -0.82 | 0.01 | 0.98 | FALSE |
| 14 | GTEx | Testis | CEP68 | 0.26 | 0.27 | lasso | 5 | 0.26 | 5.3e-12 | -7.1 | 7.0 | 1.8e-12 | -1.00 | 0.00 | 1.00 | FALSE |
| 15 | YFS | Blood | CEP68 | 0.08 | 0.10 | lasso | 7 | 0.10 | 2.9e-30 | -6.0 | 6.6 | 4.5e-11 | -0.95 | 0.01 | 0.99 | FALSE |
| 16 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CEP68 | 0.12 | 0.07 | blup | 55 | 0.06 | 1.7e-04 | -6.1 | 6.4 | 1.8e-10 | -0.92 | 0.00 | 0.99 | FALSE |
| 17 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP68 | 0.04 | 0.03 | lasso | 4 | 0.02 | 4.0e-03 | -6.9 | 7.0 | 2.9e-12 | -0.98 | 0.00 | 0.98 | FALSE |