Best TWAS P=1.76e-07 · Best GWAS P=4.44e-07 conditioned to 0.535
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | FBXO38 | 0.04 | 0.04 | blup | 52 | 0.04 | 0.0048 | -4.2 | 5.2 | 1.8e-07 | -0.92 | 0.02 | 0.46 | TRUE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | FBXO38 | 0.05 | 0.02 | lasso | 2 | 0.02 | 0.0435 | -4.8 | 5.2 | 2.4e-07 | -0.88 | 0.01 | 0.60 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FBXO38 | 0.03 | 0.01 | enet | 6 | 0.01 | 0.0501 | -4.3 | 5.2 | 2.3e-07 | -0.80 | 0.02 | 0.72 | FALSE |