Best TWAS P=4.96e-12 · Best GWAS P=6.14e-14 conditioned to 0.000127
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HOXA10 | 0.02 | 0.01 | blup | 53 | 0.01 | 0.00903 | -7.40 | 6.9 | 5.0e-12 | -0.68 | 0.00 | 0.84 | TRUE |
2 | The Cancer Genome Atlas | Esophageal Carcinoma | EVX1 | 0.16 | 0.02 | blup | 50 | 0.12 | 0.00014 | 0.41 | -5.6 | 1.9e-08 | 0.61 | 0.01 | 0.46 | FALSE |