Best TWAS P=1.98e-08 · Best GWAS P=2.56e-08 conditioned to 0.143
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | MPI | 0.14 | 0.09 | enet | 13 | 0.09 | 9.7e-04 | 5.1 | 5.6 | 2.0e-08 | 0.86 | 0.03 | 0.92 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | MPI | 0.16 | 0.00 | lasso | 8 | 0.01 | 1.4e-01 | -4.8 | 5.5 | 4.9e-08 | 0.78 | 0.04 | 0.48 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Male) | PPCDC | 0.07 | 0.00 | enet | 8 | -0.01 | 7.9e-01 | -5.2 | -5.4 | 8.0e-08 | -0.81 | 0.03 | 0.33 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | ULK3 | 0.12 | 0.02 | enet | 14 | 0.09 | 1.4e-05 | 4.2 | -5.1 | 2.9e-07 | -0.81 | 0.13 | 0.75 | FALSE |
| 5 | METSIM | Adipose | MPI | 0.08 | 0.06 | blup | 273 | 0.07 | 3.1e-11 | -3.2 | 5.2 | 1.7e-07 | 0.59 | 0.12 | 0.87 | FALSE |
| 6 | METSIM | Adipose | RPP25 | 0.04 | 0.06 | lasso | 7 | 0.05 | 1.4e-08 | -5.1 | -5.2 | 2.0e-07 | -0.76 | 0.06 | 0.94 | FALSE |
| 7 | NTR | Blood | SCAMP2 | 0.01 | 0.01 | blup | 290 | 0.01 | 1.6e-03 | 4.9 | 5.4 | 5.1e-08 | 0.66 | 0.06 | 0.74 | FALSE |