Best TWAS P=4.31e-12 · Best GWAS P=9.17e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | KCNK3 | 0.24 | 0.15 | lasso | 3 | 0.15 | 6.5e-19 | 6.8 | -6.9 | 4.3e-12 | -0.99 | 0.00 | 1.00 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SLC35F6 | 0.05 | 0.04 | enet | 11 | 0.04 | 8.0e-06 | -5.2 | 5.6 | 1.9e-08 | 0.73 | 0.23 | 0.77 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | ABHD1 | 0.18 | 0.02 | enet | 5 | 0.06 | 7.1e-04 | -3.0 | -5.3 | 1.3e-07 | -0.11 | 0.00 | 0.38 | TRUE |