Best TWAS P=1.53e-10 · Best GWAS P=1.05e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | BTD | 0.07 | 0.09 | lasso | 3 | 0.07 | 1.2e-09 | 6.0 | 6.1 | 7.8e-10 | 0.65 | 0.03 | 0.97 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | AC090945.1 | 0.10 | 0.12 | lasso | 7 | 0.11 | 2.8e-14 | 6.1 | 6.4 | 1.5e-10 | 0.97 | 0.02 | 0.98 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | BTD | 0.07 | 0.04 | enet | 9 | 0.04 | 1.6e-03 | -5.6 | 5.6 | 2.3e-08 | 0.41 | 0.01 | 0.52 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BTD | 0.04 | 0.02 | lasso | 3 | 0.02 | 6.5e-03 | 5.9 | 6.2 | 6.6e-10 | 0.70 | 0.01 | 0.75 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | BTD | 0.08 | 0.12 | lasso | 4 | 0.10 | 5.0e-10 | 5.4 | 5.8 | 8.0e-09 | 0.77 | 0.06 | 0.94 | FALSE |