Best TWAS P=4.54e-15 · Best GWAS P=5.23e-16 conditioned to 0.00013
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | TMEM161B-AS1 | 0.19 | 0.09 | lasso | 6 | 0.09 | 4.2e-04 | 3.8 | 5.3 | 1.4e-07 | -0.35 | 0.26 | 0.20 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 7.8 | 7.8 | 4.5e-15 | -0.05 | 0.03 | 0.97 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -7.5 | -6.8 | 1.5e-11 | 0.89 | 0.11 | 0.89 | TRUE |