[Hub]/) : Traits : Waist circumference :

chr6:25,296,606-26,689,223

Best TWAS P=2.73e-10 · Best GWAS P=9.1e-21 conditioned to 9.65e-14

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum U91328.19 0.21 0.25 lasso 8 0.27 3.7e-14 -5.1 5.3 9.4e-08 -0.36 1.00 0.00 FALSE
2 GTEx Adrenal Gland U91328.19 0.28 0.12 lasso 10 0.14 1.3e-05 -4.5 6.0 1.6e-09 -0.43 0.94 0.00 FALSE
3 GTEx Artery Aorta U91328.19 0.32 0.24 lasso 7 0.25 8.3e-14 -5.4 5.7 9.3e-09 -0.39 1.00 0.00 FALSE
4 GTEx Artery Tibial U91328.19 0.26 0.32 lasso 5 0.31 1.6e-24 -5.1 5.3 1.1e-07 -0.35 1.00 0.00 FALSE
5 GTEx Brain Caudate basal ganglia U91328.19 0.23 0.16 lasso 10 0.16 3.1e-05 -4.8 5.3 9.8e-08 -0.34 0.62 0.16 FALSE
6 GTEx Brain Cortex U91328.19 0.36 0.14 lasso 10 0.15 7.1e-05 -5.2 5.6 2.8e-08 -0.32 0.64 0.04 FALSE
7 GTEx Brain Frontal Cortex BA9 U91328.19 0.17 0.16 lasso 4 0.18 1.8e-05 -5.2 5.4 7.7e-08 -0.32 0.44 0.07 FALSE
8 GTEx Breast Mammary Tissue U91328.19 0.38 0.39 lasso 5 0.38 2.2e-20 -5.1 5.3 1.2e-07 -0.34 1.00 0.00 FALSE
9 GTEx Breast Mammary Tissue (Female) U91328.19 0.39 0.27 lasso 6 0.23 1.4e-07 -5.1 5.3 1.4e-07 -0.33 0.95 0.00 FALSE
10 GTEx Esophagus Gastroesophageal Junction U91328.19 0.28 0.07 lasso 7 0.21 4.3e-08 -5.2 5.6 2.4e-08 -0.35 0.71 0.02 FALSE
11 GTEx Esophagus Mucosa U91328.19 0.45 0.42 lasso 7 0.44 6.3e-32 -5.1 5.6 1.7e-08 -0.37 1.00 0.00 FALSE
12 GTEx Esophagus Muscularis U91328.19 0.36 0.30 lasso 10 0.30 1.7e-18 -5.4 5.4 8.6e-08 -0.39 1.00 0.00 FALSE
13 GTEx Heart Atrial Appendage U91328.19 0.25 0.17 enet 6 0.13 2.0e-06 -5.1 5.3 1.1e-07 -0.35 0.99 0.00 FALSE
14 GTEx Lung U91328.19 0.20 0.22 enet 15 0.24 2.9e-18 -5.5 5.8 6.4e-09 -0.37 1.00 0.00 FALSE
15 GTEx Muscle Skeletal U91328.19 0.28 0.26 enet 15 0.32 1.3e-31 -5.1 5.3 9.0e-08 -0.34 1.00 0.00 FALSE
16 GTEx Nerve Tibial U91328.19 0.46 0.38 lasso 10 0.36 1.4e-26 -5.1 5.1 2.7e-07 -0.34 1.00 0.00 FALSE
17 GTEx Ovary U91328.19 0.37 0.17 enet 18 0.34 4.7e-09 -5.2 6.3 2.7e-10 -0.40 0.73 0.04 TRUE
18 GTEx Skin Not Sun Exposed Suprapubic U91328.19 0.39 0.37 lasso 11 0.34 2.4e-19 -5.1 5.4 8.0e-08 -0.36 1.00 0.00 FALSE
19 GTEx Skin Sun Exposed Lower leg U91328.19 0.29 0.34 lasso 6 0.34 5.6e-29 -5.1 5.2 1.9e-07 -0.33 1.00 0.00 FALSE
20 GTEx Uterus U91328.19 0.38 0.05 enet 21 0.04 6.2e-02 -5.5 5.5 4.8e-08 -0.37 0.12 0.38 FALSE
21 METSIM Adipose U91328.19 0.19 0.24 lasso 23 0.25 1.7e-36 -5.1 5.4 8.0e-08 -0.34 1.00 0.00 FALSE