Best TWAS P=1.51e-09 · Best GWAS P=2.55e-09 conditioned to 0.0296
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | PHF2 | 0.07 | 0.06 | lasso | 5 | 0.04 | 0.00055 | 5.8 | 6.0 | 1.5e-09 | 0.75 | 0.01 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PHF2 | 0.02 | 0.01 | blup | 104 | 0.01 | 0.00464 | 5.7 | 5.8 | 8.3e-09 | 0.69 | 0.01 | 0.94 | FALSE |