Best TWAS P=1.81e-08 · Best GWAS P=1.62e-08 conditioned to 0.000923
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ZNHIT6 | 0.05 | 0.01 | bslmm | 552 | 0.01 | 1.9e-02 | 5.5 | -5.6 | 1.8e-08 | 0.49 | 0.07 | 0.72 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | ZNHIT6 | 0.11 | 0.12 | enet | 15 | 0.14 | 1.5e-17 | 5.3 | -5.4 | 6.2e-08 | 0.56 | 0.07 | 0.93 | FALSE |