Best TWAS P=1.15e-11 · Best GWAS P=9.26e-15 conditioned to 4.9e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC8 | 0.03 | 0.05 | enet | 5 | 0.04 | 2.4e-05 | 5.2 | -5.4 | 8.7e-08 | -0.85 | 0.08 | 0.84 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | HOXC11 | 0.09 | 0.04 | lasso | 2 | 0.03 | 9.3e-04 | -6.6 | 6.8 | 1.2e-11 | 0.38 | 0.27 | 0.07 | TRUE |