Best TWAS P=2.53e-08 · Best GWAS P=2.79e-07 conditioned to 0.0191
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | RP1-283E3.4 | 0.26 | 0.05 | enet | 25 | 0.16 | 1.5e-08 | -3.2 | -5.6 | 2.5e-08 | -0.27 | 0.09 | 0.14 | TRUE |
2 | GTEx | Brain Cerebellar Hemisphere | RP5-890O3.9 | 0.24 | 0.02 | lasso | 9 | 0.02 | 1.3e-01 | -4.8 | 5.2 | 2.2e-07 | 0.28 | 0.02 | 0.38 | TRUE |
3 | GTEx | Esophagus Mucosa | RP1-283E3.4 | 0.53 | 0.12 | enet | 20 | 0.22 | 4.1e-15 | -3.2 | -5.4 | 5.6e-08 | -0.19 | 0.62 | 0.05 | FALSE |
4 | GTEx | Esophagus Muscularis | RP1-283E3.4 | 0.46 | 0.14 | enet | 23 | 0.24 | 1.6e-14 | -3.2 | -5.4 | 7.5e-08 | -0.24 | 0.59 | 0.07 | FALSE |