[Hub]/) : Traits : Hip circumference : ← →

chr17:3,587-1,336,407

Best TWAS P=1.06e-11 · Best GWAS P=1.2e-11 conditioned to 0.143

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	VPS53	0.20	0.23	lasso	4	0.23	2.0e-18	-6.1	6.2	5.7e-10	-0.92	0.15	0.85	FALSE
2	GTEx	Adipose Visceral Omentum	VPS53	0.36	0.29	lasso	4	0.28	8.1e-15	-6.1	6.5	8.3e-11	-0.93	0.15	0.85	FALSE
3	GTEx	Artery Aorta	VPS53	0.29	0.16	lasso	3	0.18	2.3e-10	-6.0	6.1	8.7e-10	-0.85	0.17	0.83	FALSE
4	GTEx	Artery Coronary	VPS53	0.68	0.28	lasso	14	0.25	5.3e-09	-6.0	5.8	6.4e-09	-0.88	0.16	0.83	FALSE
5	GTEx	Artery Tibial	VPS53	0.23	0.14	lasso	5	0.14	3.7e-11	-6.0	5.2	1.9e-07	-0.85	0.19	0.81	FALSE
6	GTEx	Brain Caudate basal ganglia	VPS53	0.26	0.21	lasso	6	0.17	1.1e-05	-6.0	5.5	4.0e-08	-0.81	0.07	0.79	FALSE
7	GTEx	Brain Cerebellum	VPS53	0.49	0.25	lasso	7	0.22	3.8e-07	-6.1	6.3	3.7e-10	-0.88	0.04	0.95	FALSE
8	GTEx	Brain Nucleus accumbens basal ganglia	VPS53	0.43	0.30	lasso	2	0.28	2.7e-08	-6.1	6.1	1.4e-09	-0.92	0.09	0.88	FALSE
9	GTEx	Breast Mammary Tissue	VPS53	0.46	0.35	lasso	4	0.35	5.5e-19	-6.1	6.2	4.8e-10	-0.91	0.16	0.84	FALSE
10	GTEx	Breast Mammary Tissue (Male)	VPS53	0.28	0.24	lasso	2	0.22	7.6e-06	-6.0	6.1	1.3e-09	-0.92	0.06	0.54	FALSE
11	GTEx	Breast Mammary Tissue (Female)	VPS53	0.36	0.21	lasso	5	0.22	3.9e-07	-6.1	5.9	3.1e-09	-0.83	0.06	0.86	FALSE
12	GTEx	Cells Transformed fibroblasts	VPS53	0.27	0.18	lasso	3	0.20	8.7e-15	-6.1	5.8	6.9e-09	-0.87	0.14	0.86	FALSE
13	GTEx	Colon Sigmoid	VPS53	0.35	0.19	lasso	5	0.19	3.9e-07	-6.1	6.1	1.3e-09	-0.93	0.10	0.88	FALSE
14	GTEx	Colon Transverse	VPS53	0.31	0.15	lasso	7	0.18	3.7e-09	-6.0	5.6	2.4e-08	-0.83	0.16	0.82	FALSE
15	GTEx	Esophagus Gastroesophageal Junction	VPS53	0.62	0.24	enet	54	0.29	3.3e-11	-5.8	5.5	4.6e-08	-0.67	0.20	0.80	FALSE
16	GTEx	Esophagus Muscularis	VPS53	0.37	0.21	lasso	10	0.21	1.1e-12	-6.1	6.5	9.8e-11	-0.90	0.13	0.87	FALSE
17	GTEx	Heart Atrial Appendage	VPS53	0.31	0.20	lasso	3	0.22	2.1e-10	-6.1	6.8	1.1e-11	-0.91	0.12	0.88	TRUE
18	GTEx	Heart Left Ventricle	VPS53	0.26	0.20	lasso	4	0.18	3.7e-10	-6.0	6.3	3.5e-10	-0.93	0.14	0.86	FALSE
19	GTEx	Lung	VPS53	0.33	0.31	enet	23	0.34	5.6e-27	-6.1	5.9	2.9e-09	-0.91	0.14	0.86	FALSE
20	GTEx	Muscle Skeletal	VPS53	0.15	0.09	lasso	4	0.08	1.1e-08	5.8	6.1	1.1e-09	-0.71	0.16	0.84	FALSE
21	GTEx	Nerve Tibial	VPS53	0.37	0.35	enet	14	0.37	2.1e-27	-6.1	6.0	1.8e-09	-0.84	0.15	0.85	FALSE
22	GTEx	Ovary	VPS53	0.65	0.26	lasso	11	0.18	4.3e-05	-6.0	5.8	8.8e-09	-0.89	0.04	0.92	FALSE
23	GTEx	Pancreas	VPS53	0.43	0.35	lasso	4	0.37	2.3e-16	-6.0	6.5	8.0e-11	-0.92	0.18	0.82	FALSE
24	GTEx	Pituitary	VPS53	0.32	0.19	lasso	7	0.19	1.9e-05	-6.1	6.1	1.0e-09	-0.90	0.02	0.90	FALSE
25	GTEx	Prostate	VPS53	0.54	0.37	enet	19	0.34	2.0e-09	-6.1	5.4	6.3e-08	-0.85	0.10	0.89	FALSE
26	GTEx	Skin Not Sun Exposed Suprapubic	VPS53	0.34	0.32	lasso	1	0.31	1.0e-17	-6.1	6.1	1.3e-09	-0.92	0.15	0.85	FALSE
27	GTEx	Skin Sun Exposed Lower leg	VPS53	0.18	0.14	lasso	4	0.14	1.3e-11	-6.1	5.8	8.2e-09	-0.89	0.15	0.85	FALSE
28	GTEx	Spleen	VPS53	0.52	0.45	lasso	5	0.44	1.5e-12	-6.1	6.3	3.3e-10	-0.92	0.15	0.85	FALSE
29	GTEx	Stomach	VPS53	0.43	0.12	lasso	8	0.15	1.2e-07	-6.0	5.3	9.2e-08	-0.80	0.17	0.81	FALSE
30	GTEx	Testis	VPS53	0.30	0.13	lasso	6	0.19	8.7e-09	-6.0	5.7	1.2e-08	-0.83	0.14	0.86	FALSE
31	GTEx	Thyroid	VPS53	0.40	0.42	enet	16	0.45	1.2e-37	-6.1	6.5	7.9e-11	-0.91	0.14	0.86	FALSE
32	METSIM	Adipose	FAM57A	0.04	0.04	lasso	3	0.03	5.8e-05	6.2	5.8	7.0e-09	-0.52	0.20	0.78	FALSE
33	YFS	Blood	VPS53	0.21	0.29	enet	13	0.34	2.9e-114	-6.1	6.0	1.8e-09	-0.91	0.22	0.78	FALSE
34	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FAM101B	0.07	0.03	blup	74	0.05	1.1e-03	-6.3	-6.5	7.9e-11	0.75	0.03	0.80	FALSE