Best TWAS P=5.27e-08 · Best GWAS P=6.2e-07 conditioned to 0.162
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | GGCX | 0.29 | 0.22 | enet | 14 | 0.24 | 6.3e-19 | 4.5 | 5.3 | 1.1e-07 | 0.85 | 0.02 | 0.95 | FALSE |
2 | GTEx | Skin Not Sun Exposed Suprapubic | GGCX | 0.13 | 0.04 | enet | 11 | 0.06 | 3.9e-04 | 4.4 | 5.4 | 5.3e-08 | 0.74 | 0.01 | 0.91 | TRUE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GGCX | 0.04 | 0.02 | blup | 44 | 0.02 | 2.7e-03 | 3.7 | 5.1 | 2.9e-07 | 0.72 | 0.03 | 0.74 | FALSE |