[Hub]/) : Traits : Hip circumference : ← →

chr2:171,596,034-173,555,880

Best TWAS P=1.25e-17 · Best GWAS P=2.05e-16 conditioned to 0.638

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CYBRD1	0.33	0.18	lasso	7	0.27	5.2e-33	5.1	7.3	3.1e-13	-0.69	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	CYBRD1	0.35	0.19	lasso	6	0.24	7.3e-20	-6.4	7.8	4.5e-15	-0.77	0.01	0.99	FALSE
3	GTEx	Adipose Subcutaneous	DYNC1I2	0.13	0.11	enet	13	0.11	4.1e-09	-5.8	5.8	8.9e-09	-0.29	0.09	0.91	FALSE
4	GTEx	Adipose Visceral Omentum	CYBRD1	0.33	0.10	lasso	10	0.26	4.6e-14	-6.6	8.0	1.7e-15	-0.71	0.01	0.99	FALSE
5	GTEx	Artery Aorta	CYBRD1	0.52	0.30	lasso	10	0.41	6.0e-24	5.1	7.5	6.8e-14	-0.66	0.47	0.53	FALSE
6	GTEx	Artery Aorta	SLC25A12	0.13	0.03	lasso	16	0.01	1.2e-01	-5.7	-5.3	9.0e-08	0.27	0.09	0.85	FALSE
7	GTEx	Artery Coronary	CYBRD1	0.29	0.01	enet	44	0.11	2.0e-04	-6.6	5.8	5.9e-09	-0.68	0.02	0.80	FALSE
8	GTEx	Artery Tibial	CYBRD1	0.37	0.08	lasso	9	0.21	3.0e-16	-5.8	7.9	2.1e-15	-0.75	0.03	0.97	FALSE
9	GTEx	Artery Tibial	SLC25A12	0.11	0.09	lasso	8	0.06	8.4e-06	-5.6	-5.5	4.9e-08	0.28	0.08	0.92	FALSE
10	GTEx	Brain Cerebellar Hemisphere	DYNC1I2	0.32	0.24	lasso	7	0.26	2.0e-07	-4.8	5.7	1.4e-08	-0.27	0.10	0.89	FALSE
11	GTEx	Breast Mammary Tissue	CYBRD1	0.32	0.21	enet	16	0.27	2.0e-14	-6.4	8.4	5.2e-17	-0.74	0.01	0.99	FALSE
12	GTEx	Breast Mammary Tissue (Male)	CYBRD1	0.35	0.24	lasso	6	0.20	2.4e-05	-6.4	7.2	8.4e-13	-0.72	0.02	0.76	FALSE
13	GTEx	Breast Mammary Tissue (Female)	CYBRD1	0.20	0.07	lasso	2	0.14	4.5e-05	-6.4	7.9	2.9e-15	-0.78	0.01	0.93	FALSE
14	GTEx	Cells Transformed fibroblasts	CYBRD1	0.34	0.16	enet	27	0.26	6.3e-20	-6.6	7.0	1.8e-12	-0.57	0.00	1.00	FALSE
15	GTEx	Cells Transformed fibroblasts	DYNC1I2	0.12	0.14	lasso	3	0.14	1.4e-10	-6.1	6.1	1.1e-09	-0.29	0.08	0.92	FALSE
16	GTEx	Esophagus Muscularis	CYBRD1	0.33	0.07	lasso	9	0.22	1.3e-13	-5.8	8.2	3.6e-16	-0.75	0.02	0.98	FALSE
17	GTEx	Lung	CYBRD1	0.14	0.05	enet	8	0.10	5.6e-08	3.2	5.3	1.4e-07	-0.45	0.99	0.00	FALSE
18	GTEx	Muscle Skeletal	CYBRD1	0.10	0.00	enet	9	0.01	1.5e-02	-6.4	7.2	8.8e-13	-0.71	0.02	0.90	FALSE
19	GTEx	Muscle Skeletal	DYNC1I2	0.11	0.12	lasso	2	0.12	6.5e-12	-6.2	6.3	3.1e-10	-0.30	0.06	0.94	FALSE
20	GTEx	Nerve Tibial	CYBRD1	0.36	0.07	lasso	10	0.20	2.3e-14	-6.4	8.0	9.5e-16	-0.73	0.02	0.98	FALSE
21	GTEx	Skin Sun Exposed Lower leg	DYNC1I2	0.11	0.16	lasso	1	0.15	8.9e-13	-6.1	6.1	1.3e-09	-0.29	0.08	0.92	FALSE
22	GTEx	Spleen	DCAF17	0.34	0.01	lasso	10	0.07	7.9e-03	5.4	5.2	2.4e-07	-0.22	0.07	0.06	TRUE
23	GTEx	Testis	DYNC1I2	0.13	0.02	lasso	4	0.01	1.1e-01	-6.2	6.0	1.4e-09	-0.29	0.07	0.63	FALSE
24	GTEx	Thyroid	CYBRD1	0.26	0.08	enet	26	0.12	1.4e-09	-6.4	6.6	3.1e-11	-0.72	0.02	0.98	FALSE
25	GTEx	Uterus	CYBRD1	0.54	0.04	lasso	6	0.19	1.1e-04	6.3	6.9	4.3e-12	-0.49	0.02	0.74	FALSE
26	GTEx	Whole Blood	CYBRD1	0.25	0.14	enet	19	0.15	1.4e-13	5.2	5.7	1.4e-08	-0.52	0.95	0.05	FALSE
27	ROSMAP	Brain Pre-frontal Cortex	CYBRD1	0.37	0.16	lasso	9	0.30	3.0e-39	-5.6	7.7	1.4e-14	-0.77	0.30	0.70	FALSE
28	ROSMAP	Brain Pre-frontal Cortex	SLC25A12	0.13	0.08	lasso	6	0.11	1.8e-13	-6.1	-5.3	8.8e-08	0.28	1.00	0.00	FALSE
29	ROSMAP	Brain Pre-frontal Cortex	AC068039.4	0.43	0.64	enet	35	0.65	1.6e-110	-6.1	-6.4	1.5e-10	0.29	1.00	0.00	FALSE
30	YFS	Blood	SLC25A12	0.09	0.15	lasso	7	0.15	1.3e-45	-6.1	-6.2	7.9e-10	0.29	1.00	0.00	FALSE
31	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CYBRD1	0.14	0.04	enet	12	0.09	2.2e-05	-8.2	-7.7	2.1e-14	0.78	0.00	0.96	FALSE
32	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DYNC1I2	0.05	0.06	lasso	4	0.05	6.3e-06	-6.2	5.8	7.4e-09	-0.26	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	CYBRD1	0.03	0.02	lasso	3	0.03	4.5e-04	5.1	6.3	3.1e-10	-0.46	0.18	0.21	FALSE
34	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MAP1D	0.03	0.03	lasso	2	0.02	1.5e-03	-5.5	5.4	6.4e-08	-0.21	0.01	0.94	FALSE
35	The Cancer Genome Atlas	Prostate Adenocarcinoma	CYBRD1	0.08	0.06	blup	68	0.08	1.5e-08	-5.6	6.1	8.8e-10	-0.51	0.94	0.06	FALSE
36	The Cancer Genome Atlas	Thyroid Carcinoma	CYBRD1	0.10	0.06	lasso	4	0.06	6.2e-07	-6.4	8.6	1.2e-17	-0.86	0.00	1.00	TRUE