Best TWAS P=9.5e-15 · Best GWAS P=2.17e-15 conditioned to 2.26e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | TMEM161B-AS1 | 0.19 | 0.09 | lasso | 6 | 0.09 | 4.2e-04 | 3.5 | 5.1 | 2.7e-07 | 0.36 | 0.25 | 0.23 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 7.7 | 7.8 | 9.5e-15 | 0.95 | 0.00 | 1.00 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -6.0 | -5.2 | 1.7e-07 | 0.13 | 1.00 | 0.00 | TRUE |