Best TWAS P=1.23e-10 · Best GWAS P=6.23e-11 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | FIGNL1 | 0.31 | 0.27 | enet | 13 | 0.30 | 9.4e-17 | -4.9 | -5.7 | 1.3e-08 | 0.86 | 0.04 | 0.96 | FALSE |
2 | GTEx | Brain Frontal Cortex BA9 | FIGNL1 | 0.24 | 0.19 | enet | 9 | 0.25 | 2.2e-07 | 3.3 | -5.3 | 1.3e-07 | 0.87 | 0.04 | 0.96 | FALSE |
3 | GTEx | Heart Atrial Appendage | FIGNL1 | 0.30 | 0.28 | lasso | 7 | 0.27 | 1.2e-12 | -4.9 | -5.4 | 5.5e-08 | 0.74 | 0.06 | 0.94 | FALSE |
4 | GTEx | Heart Left Ventricle | FIGNL1 | 0.12 | 0.10 | lasso | 4 | 0.12 | 5.2e-07 | -4.5 | -5.3 | 1.3e-07 | 0.84 | 0.02 | 0.98 | FALSE |
5 | GTEx | Prostate | FIGNL1 | 0.52 | 0.29 | enet | 13 | 0.40 | 2.6e-11 | -6.5 | -5.6 | 2.4e-08 | 0.89 | 0.00 | 1.00 | FALSE |
6 | GTEx | Skin Not Sun Exposed Suprapubic | FIGNL1 | 0.47 | 0.37 | enet | 24 | 0.43 | 1.8e-25 | -6.4 | -5.5 | 2.8e-08 | 0.87 | 0.00 | 1.00 | FALSE |
7 | GTEx | Small Intestine Terminal Ileum | FIGNL1 | 0.21 | 0.23 | lasso | 4 | 0.22 | 1.3e-05 | -6.5 | -6.4 | 1.2e-10 | 0.98 | 0.01 | 0.97 | TRUE |
8 | GTEx | Testis | FIGNL1 | 0.35 | 0.24 | enet | 28 | 0.27 | 3.0e-12 | -4.9 | -5.2 | 2.5e-07 | 0.84 | 0.01 | 0.99 | FALSE |
9 | The Cancer Genome Atlas | Stomach Adenocarcinoma | FIGNL1 | 0.05 | 0.00 | blup | 68 | 0.01 | 5.4e-02 | -6.4 | -5.1 | 2.9e-07 | 0.78 | 0.00 | 0.73 | FALSE |