[Hub]/) : Traits : Pain experienced in last month :

chr3:48,702,606-50,636,111

Best TWAS P=1.52e-08 · Best GWAS P=3.19e-07 conditioned to 0.0132

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RNF123 0.19 0.18 enet 29 0.18 2.1e-14 4.6 5.2 1.7e-07 0.77 0.16 0.82 FALSE
2 GTEx Artery Tibial MST1R 0.06 0.02 lasso 5 0.02 1.5e-02 4.7 5.1 3.3e-07 0.76 0.08 0.53 FALSE
3 GTEx Artery Tibial IP6K1 0.03 0.00 enet 22 0.01 2.5e-02 4.9 5.3 1.5e-07 0.70 0.09 0.60 FALSE
4 GTEx Brain Cerebellum MST1R 0.19 0.24 enet 22 0.20 1.8e-06 -4.3 5.1 2.9e-07 0.83 0.12 0.85 FALSE
5 GTEx Brain Cerebellum GPX1 0.31 0.09 enet 19 0.23 2.0e-07 -4.8 5.4 7.8e-08 0.43 0.04 0.94 FALSE
6 GTEx Brain Frontal Cortex BA9 RNF123 0.25 0.28 enet 34 0.05 2.3e-02 4.6 5.1 3.5e-07 0.74 0.17 0.78 FALSE
7 GTEx Brain Frontal Cortex BA9 GPX1 0.16 0.06 lasso 6 0.15 7.9e-05 4.0 5.6 2.3e-08 0.38 0.06 0.77 FALSE
8 GTEx Esophagus Muscularis GPX1 0.13 0.05 lasso 14 0.06 1.1e-04 -4.8 5.5 3.3e-08 0.40 0.04 0.94 FALSE
9 GTEx Heart Left Ventricle DAG1 0.06 0.02 enet 14 0.02 3.2e-02 3.8 -5.2 2.6e-07 -0.63 0.25 0.28 FALSE
10 GTEx Lung GPX1 0.04 0.02 enet 13 0.04 5.7e-04 -4.7 5.7 1.5e-08 0.53 0.06 0.71 TRUE
11 METSIM Adipose MST1R 0.03 0.02 blup 331 0.02 1.7e-03 4.8 5.5 3.9e-08 0.88 0.05 0.94 FALSE
12 ROSMAP Brain Pre-frontal Cortex MST1R 0.02 0.00 blup 278 0.01 4.5e-02 4.8 5.3 1.2e-07 0.81 0.12 0.80 FALSE
13 TCGA Ovarian Tumor ACTBP13 0.02 0.01 blup 270 0.02 8.2e-03 3.0 -5.2 1.9e-07 -0.82 0.14 0.49 FALSE