Best TWAS P=9.26e-12 · Best GWAS P=3.96e-13 conditioned to 0.000299
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CTBP2 | 0.06 | 0.02 | lasso | 2 | 0.04 | 4.4e-06 | 7.2 | 6.6 | 5.2e-11 | -0.37 | 0.00 | 0.99 | FALSE |
2 | GTEx | Thyroid | METTL10 | 0.19 | 0.09 | enet | 33 | 0.10 | 3.0e-08 | -4.3 | -5.4 | 8.1e-08 | -0.02 | 1.00 | 0.00 | TRUE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CTBP2 | 0.09 | 0.03 | enet | 14 | 0.09 | 6.2e-10 | 4.8 | 6.8 | 9.3e-12 | -0.70 | 0.03 | 0.97 | TRUE |