Best TWAS P=2.85e-08 · Best GWAS P=2.05e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | OGFOD1 | 0.11 | 0.06 | lasso | 1 | 0.05 | 1.1e-04 | 5.6 | -5.5 | 2.9e-08 | -0.99 | 0.00 | 0.99 | TRUE |
2 | METSIM | Adipose | OGFOD1 | 0.07 | 0.05 | lasso | 5 | 0.05 | 4.6e-08 | 5.5 | -5.5 | 4.2e-08 | -0.96 | 0.01 | 0.99 | FALSE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | OGFOD1 | 0.04 | 0.03 | lasso | 4 | 0.02 | 1.5e-03 | 5.3 | -5.5 | 2.9e-08 | -0.89 | 0.02 | 0.87 | FALSE |