Best TWAS P=9.53e-08 · Best GWAS P=2.01e-07 conditioned to 0.499
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | RAB23 | 0.04 | 0.02 | enet | 14 | 0.01 | 1.7e-02 | 5.0 | 5.2 | 2.1e-07 | 0.87 | 0.02 | 0.94 | FALSE |
| 2 | YFS | Blood | RAB23 | 0.11 | 0.24 | enet | 19 | 0.24 | 1.9e-77 | 5.0 | 5.1 | 2.8e-07 | 0.86 | 0.03 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Rectum Adenocarcinoma | BEND6 | 0.20 | 0.15 | blup | 44 | 0.18 | 6.4e-05 | 4.4 | -5.3 | 9.5e-08 | -0.93 | 0.03 | 0.87 | TRUE |