Best TWAS P=7.56e-10 · Best GWAS P=9.31e-13 conditioned to 3.83e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CHDH | 0.10 | 0.04 | enet | 12 | 0.08 | 4.0e-07 | -6.9 | 5.6 | 1.7e-08 | -0.57 | 0.06 | 0.94 | FALSE |
| 2 | GTEx | Nerve Tibial | CHDH | 0.31 | 0.22 | enet | 13 | 0.28 | 3.2e-20 | -4.9 | 6.2 | 7.6e-10 | -0.65 | 0.66 | 0.34 | TRUE |
| 3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | CHDH | 0.11 | 0.01 | blup | 78 | 0.09 | 5.1e-04 | -7.1 | 5.2 | 2.1e-07 | -0.75 | 0.01 | 0.86 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | CHDH | 0.14 | 0.07 | blup | 78 | 0.09 | 1.9e-09 | -4.7 | 5.8 | 5.1e-09 | -0.62 | 0.36 | 0.64 | FALSE |