Best TWAS P=1.06e-18 · Best GWAS P=2.36e-15 conditioned to 0.382
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | ELF2 | 0.26 | 0.03 | lasso | 7 | 0.04 | 2.8e-02 | 5.2 | 5.2 | 1.7e-07 | -0.47 | 0.25 | 0.09 | FALSE |
| 2 | GTEx | Lung | NDUFC1 | 0.09 | 0.07 | lasso | 5 | 0.06 | 3.6e-05 | -4.5 | -5.3 | 1.4e-07 | 0.73 | 0.14 | 0.84 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | MGARP | 0.08 | 0.02 | blup | 400 | 0.03 | 8.4e-05 | 5.7 | 6.2 | 4.1e-10 | -0.59 | 0.81 | 0.15 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ELF2 | 0.03 | 0.00 | blup | 51 | 0.01 | 1.1e-02 | -7.9 | 8.8 | 1.1e-18 | -0.84 | 0.01 | 0.89 | TRUE |