Best TWAS P=5.77e-13 · Best GWAS P=2.71e-16 conditioned to 7.15e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TCF4 | 0.06 | 0.00 | enet | 4 | 0.00 | 0.5070 | 4.3 | -5.7 | 1.5e-08 | 0.14 | 0.24 | 0.04 | TRUE |
| 2 | METSIM | Adipose | RP11-397A16.2 | 0.03 | 0.01 | bslmm | 422 | 0.01 | 0.0076 | 3.5 | 7.2 | 5.8e-13 | -0.45 | 0.15 | 0.61 | TRUE |