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chr19:54,008,019-55,427,510

Best TWAS P=7.9e-12 · Best GWAS P=8.14e-13 conditioned to 0.0124

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RPS9 0.32 0.16 lasso 9 0.28 1.5e-34 -6.5 5.2 1.6e-07 -0.02 0.14 0.86 FALSE
2 GTEx Artery Aorta RPS9 0.39 0.27 enet 13 0.34 2.4e-19 -6.5 5.3 9.0e-08 -0.03 0.14 0.86 FALSE
3 GTEx Brain Cerebellum RPS9 0.72 0.14 lasso 17 0.20 1.1e-06 2.1 5.3 9.0e-08 0.02 0.56 0.24 TRUE
4 GTEx Colon Sigmoid LILRA6 0.32 0.14 lasso 6 0.10 1.7e-04 -4.6 5.9 4.0e-09 0.40 0.09 0.37 TRUE
5 GTEx Esophagus Muscularis RPS9 0.50 0.28 lasso 8 0.36 1.5e-22 -6.5 5.4 5.9e-08 -0.05 0.14 0.86 FALSE
6 GTEx Nerve Tibial RPS9 0.37 0.19 lasso 12 0.23 2.8e-16 -6.5 5.6 2.6e-08 -0.02 0.14 0.86 FALSE
7 GTEx Stomach RPS9 0.43 0.18 lasso 12 0.17 1.5e-08 -6.5 5.5 4.5e-08 -0.08 0.14 0.86 FALSE
8 YFS Blood LILRB2 0.04 0.02 enet 18 0.02 1.1e-07 5.8 -5.3 1.0e-07 -0.51 0.35 0.64 FALSE
9 YFS Blood RPS9 0.39 0.32 lasso 11 0.44 1.9e-160 -6.5 5.2 1.9e-07 -0.02 0.01 0.99 FALSE
10 The Cancer Genome Atlas Esophageal Carcinoma LILRB3 0.19 0.07 blup 6 0.09 1.0e-03 2.9 -6.8 7.9e-12 -0.38 0.00 0.09 TRUE
11 The Cancer Genome Atlas Lung Adenocarcinoma LILRB3 0.13 0.13 enet 5 0.15 1.5e-17 2.9 -5.2 2.1e-07 -0.19 1.00 0.00 FALSE