[Hub]/) : Traits : Neuroticism :

chr5:86,867,897-88,677,293

Best TWAS P=1.25e-09 · Best GWAS P=9.1e-11 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cortex TMEM161B-AS1 0.35 0.15 lasso 15 0.30 6.5e-09 4.2 5.4 7.9e-08 0.30 0.77 0.04 TRUE
2 GTEx Brain Hippocampus TMEM161B-AS1 0.17 0.10 enet 13 0.08 5.4e-03 5.1 5.4 5.7e-08 0.21 0.12 0.07 TRUE
3 ROSMAP Brain Pre-frontal Cortex LINC00461 0.10 0.07 lasso 2 0.05 4.5e-07 6.1 6.1 1.3e-09 0.89 0.01 0.98 TRUE
4 ROSMAP Brain Pre-frontal Cortex TMEM161B-AS1 0.05 0.02 lasso 6 0.04 2.1e-05 3.8 5.5 5.0e-08 0.24 0.89 0.03 TRUE