[Hub]/) : Traits : Neuroticism :

chr9:95,186,937-96,898,436

Best TWAS P=2.16e-08 · Best GWAS P=3.43e-09 conditioned to 0.131

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta RP11-165J3.6 0.23 0.22 enet 10 0.22 2.3e-12 5.4 5.3 9.1e-08 -0.26 0.12 0.88 FALSE
2 GTEx Artery Tibial RP11-165J3.6 0.22 0.20 lasso 2 0.19 4.9e-15 5.4 5.4 5.1e-08 -0.26 0.08 0.92 FALSE
3 GTEx Brain Frontal Cortex BA9 RP11-165J3.6 0.41 0.14 lasso 6 0.20 6.1e-06 5.4 5.2 2.6e-07 -0.17 0.09 0.86 FALSE
4 GTEx Breast Mammary Tissue RP11-165J3.6 0.28 0.11 enet 24 0.13 2.7e-07 5.3 5.2 2.4e-07 -0.15 0.15 0.85 TRUE
5 GTEx Breast Mammary Tissue (Female) RP11-165J3.6 0.21 0.02 lasso 3 0.00 2.3e-01 5.3 5.4 5.7e-08 -0.27 0.06 0.20 FALSE
6 GTEx Colon Transverse RP11-165J3.6 0.37 0.20 lasso 4 0.18 3.6e-09 5.4 5.3 1.4e-07 -0.19 0.10 0.90 FALSE
7 GTEx Esophagus Gastroesophageal Junction RP11-165J3.6 0.34 0.26 lasso 8 0.27 3.0e-10 5.4 5.5 3.1e-08 -0.27 0.09 0.90 FALSE
8 GTEx Heart Atrial Appendage RP11-165J3.6 0.38 0.21 lasso 7 0.25 8.7e-12 5.1 5.5 4.7e-08 -0.26 0.09 0.91 FALSE
9 GTEx Lung RP11-165J3.6 0.25 0.16 lasso 7 0.17 4.1e-13 5.4 5.6 2.2e-08 -0.29 0.10 0.90 TRUE
10 GTEx Pituitary RP11-165J3.6 0.49 0.22 lasso 8 0.29 6.9e-08 5.3 5.1 3.6e-07 -0.17 0.09 0.87 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic RP11-165J3.6 0.27 0.14 lasso 7 0.19 1.4e-10 5.5 5.3 1.0e-07 -0.20 0.07 0.93 FALSE
12 GTEx Skin Sun Exposed Lower leg RP11-165J3.6 0.32 0.27 lasso 5 0.35 6.8e-30 5.3 5.5 4.7e-08 -0.24 0.09 0.91 FALSE
13 GTEx Thyroid RP11-165J3.6 0.35 0.27 lasso 3 0.29 1.2e-22 5.4 5.5 4.3e-08 -0.30 0.12 0.88 FALSE
14 TCGA Breast Tumor NINJ1 0.40 0.00 blup 431 0.07 1.2e-02 -5.5 -5.1 3.0e-07 0.66 0.03 0.71 TRUE