[Hub]/) : Traits : Neuroticism :

chr10:103,905,779-105,647,095

Best TWAS P=1.17e-08 · Best GWAS P=6.67e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue (Female) CYP17A1-AS1 0.14 0.01 lasso 11 0.00 4.7e-01 -5.5 -5.7 1.4e-08 0.88 0.04 0.50 FALSE
2 GTEx Esophagus Gastroesophageal Junction CYP17A1-AS1 0.23 0.08 enet 23 0.13 1.9e-05 -3.9 -5.2 2.2e-07 0.63 0.15 0.40 FALSE
3 GTEx Testis CYP17A1-AS1 0.14 0.08 enet 5 0.10 2.3e-05 -5.6 5.6 2.5e-08 -0.98 0.03 0.96 FALSE
4 ROSMAP Brain Pre-frontal Cortex CNNM2 0.11 0.08 lasso 3 0.07 2.2e-09 -5.7 -5.7 1.2e-08 1.00 0.02 0.98 TRUE
5 YFS Blood NT5C2 0.13 0.10 bslmm 382 0.11 7.3e-35 -5.6 -5.1 3.1e-07 0.94 0.02 0.98 FALSE